Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 374451..375205 Replicon chromosome
Accession NZ_LT795502
Organism Escherichia coli strain KV7 isolate KV7

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag KJB12_RS01710 Protein ID WP_001301452.1
Coordinates 374451..374936 (-) Length 162 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag KJB12_RS01715 Protein ID WP_000801914.1
Coordinates 374927..375205 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KJB12_RS01690 (369618) 369618..370376 + 759 WP_000815099.1 DeoR/GlpR family transcriptional regulator -
KJB12_RS01695 (370358) 370358..371956 - 1599 WP_071337529.1 DNA-binding transcriptional regulator RtcR -
KJB12_RS01700 (372143) 372143..373369 + 1227 WP_001105465.1 RNA-splicing ligase RtcB -
KJB12_RS01705 (373373) 373373..374401 + 1029 WP_024257792.1 RNA 3'-terminal phosphate cyclase -
KJB12_RS01710 (374451) 374451..374936 - 486 WP_001301452.1 GNAT family N-acetyltransferase Toxin
KJB12_RS01715 (374927) 374927..375205 - 279 WP_000801914.1 DUF1778 domain-containing protein Antitoxin
KJB12_RS01720 (375272) 375272..377977 - 2706 WP_000906970.1 HTH-type transcriptional regulator MalT -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(45-143)

Antitoxin

Vibrio phage ICP1, Orf50

(2-92)


Sequences

Toxin        


Download         Length: 162 a.a.        Molecular weight: 17650.57 Da        Isoelectric Point: 9.4066

>T293460 WP_001301452.1 NZ_LT795502:c374936-374451 [Escherichia coli]
MGITAPTPLTSEHNLADFCCSDHGMNEWLKKKALKNHSSGLSRVYVICIANTRQVIGYYCLSTGSIQRNLAPGAMRRNAP
ESLPVVVLGRLAIDQAWAGKGLGVALLKDAVYRTMSIAQQVGVRALIVHALDDSVRNFYLKYAFVPSPFQSLTLLYPITL
E

Download         Length: 486 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10406.91 Da        Isoelectric Point: 4.6336

>AT293460 WP_000801914.1 NZ_LT795502:c375205-374927 [Escherichia coli]
MKPESKEAPINIRAKASQRDLIDMAANLVAKSRTDFMLDAACREAQDILLDQRLFIVDDEQYDAFLAALDAPITAERQAK
INALMNRKSPWE

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References