Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PemK-DinJ
Location 1468345..1468897 Replicon chromosome
Accession NZ_LT706985
Organism Propionimicrobium sp. Marseille-P3275 strain Marseille-P3275T

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag CZ356_RS07005 Protein ID WP_076389272.1
Coordinates 1468571..1468897 (+) Length 109 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag CZ356_RS07000 Protein ID WP_076389271.1
Coordinates 1468345..1468581 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CZ356_RS06970 1463689..1464345 - 657 WP_076389268.1 alpha/beta fold hydrolase -
CZ356_RS06975 1464342..1464935 - 594 WP_076389269.1 DUF1700 domain-containing protein -
CZ356_RS06980 1464938..1465270 - 333 WP_076389916.1 PadR family transcriptional regulator -
CZ356_RS06985 1465417..1466043 - 627 WP_197684241.1 recombinase zinc beta ribbon domain-containing protein -
CZ356_RS09640 1466151..1466315 - 165 WP_156874602.1 hypothetical protein -
CZ356_RS06990 1466543..1467979 + 1437 WP_076389270.1 putative DNA binding domain-containing protein -
CZ356_RS06995 1468051..1468200 + 150 Protein_1351 toxin-antitoxin system subunit antitoxin -
CZ356_RS07000 1468345..1468581 + 237 WP_076389271.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
CZ356_RS07005 1468571..1468897 + 327 WP_076389272.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
CZ356_RS07010 1469275..1470492 - 1218 WP_076389273.1 DUF4143 domain-containing protein -
CZ356_RS07015 1470901..1472181 + 1281 WP_076389274.1 DUF4143 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-104)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-51)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 11206.96 Da        Isoelectric Point: 8.7596

>T293452 WP_076389272.1 NZ_LT706985:1468571-1468897 [Propionimicrobium sp. Marseille-P3275]
MRGEIWTVCASGYASKPRPAVIVQADSVVGFDSTIVCLFTTDDSLKGATRVSVKATGGNGLTKDCIVMAEKPVAINKSRL
GEKLGALEAETLSKVGSALRQVFGFGVG

Download         Length: 327 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8788.84 Da        Isoelectric Point: 4.3063

>AT293452 WP_076389271.1 NZ_LT706985:1468345-1468581 [Propionimicrobium sp. Marseille-P3275]
MVQLATRVDDEDGKTFKDLTKRLGTTPADAIRMFVMAFNANRGFPYEVRLSDAQPFESEKEAVNFIDDLATETISDAR

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References