Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 906728..907314 Replicon chromosome
Accession NZ_LT706985
Organism Propionimicrobium sp. Marseille-P3275 strain Marseille-P3275T

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag CZ356_RS04360 Protein ID WP_197684252.1
Coordinates 907006..907314 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CZ356_RS04355 Protein ID WP_076388868.1
Coordinates 906728..907015 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CZ356_RS04330 902496..903194 - 699 WP_076388863.1 hypothetical protein -
CZ356_RS04335 903245..904534 + 1290 WP_076388864.1 magnesium transporter -
CZ356_RS04340 904527..905015 + 489 WP_076388865.1 DUF1003 domain-containing protein -
CZ356_RS04345 905212..906357 + 1146 Protein_845 Mrp/NBP35 family ATP-binding protein -
CZ356_RS04350 906412..906597 - 186 WP_076388867.1 50S ribosomal protein L28 -
CZ356_RS04355 906728..907015 - 288 WP_076388868.1 putative addiction module antidote protein Antitoxin
CZ356_RS04360 907006..907314 - 309 WP_197684252.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CZ356_RS04365 907634..909904 + 2271 WP_076388870.1 glycoside hydrolase family 3 C-terminal domain-containing protein -
CZ356_RS04370 910006..911685 - 1680 WP_076388871.1 ribonuclease J -
CZ356_RS04375 911734..912252 + 519 WP_076388872.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(10-90)

Antitoxin

Uncharacterized protein HI1420

(5-94)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11776.66 Da        Isoelectric Point: 10.2255

>T293450 WP_197684252.1 NZ_LT706985:c907314-907006 [Propionimicrobium sp. Marseille-P3275]
IKQTDVYVRWFRRLKDVRGKARINIALQRCRVADEVVGDVKSVGDGVYELRVHTGHGYRLYYMVKGKEIMLLVVGGDKSS
QRRDIEQAKKLAAEIVEEGKWQ

Download         Length: 309 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10191.47 Da        Isoelectric Point: 4.4295

>AT293450 WP_076388868.1 NZ_LT706985:c907015-906728 [Propionimicrobium sp. Marseille-P3275]
MAVTISTWDASQYLETKDDIVAYLNAAFEESDPAILQAALGDVARSRGMSAIARQAGVGRESLYKSLSQDGNPSWQTIAK
IFDALGLQLQVKVSA

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References