Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 576323..576896 Replicon chromosome
Accession NZ_LT706985
Organism Propionimicrobium sp. Marseille-P3275 strain Marseille-P3275T

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag CZ356_RS02635 Protein ID WP_076388485.1
Coordinates 576323..576670 (-) Length 116 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag CZ356_RS02640 Protein ID WP_076388487.1
Coordinates 576657..576896 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CZ356_RS02615 572546..574012 - 1467 WP_076388483.1 FtsX-like permease family protein -
CZ356_RS02620 574013..574733 - 721 Protein_515 ABC transporter ATP-binding protein -
CZ356_RS02625 574848..575570 + 723 WP_197684248.1 sensor histidine kinase -
CZ356_RS02630 575563..576234 + 672 WP_076389753.1 response regulator transcription factor -
CZ356_RS02635 576323..576670 - 348 WP_076388485.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
CZ356_RS02640 576657..576896 - 240 WP_076388487.1 ribbon-helix-helix domain-containing protein Antitoxin
CZ356_RS02645 577610..578317 + 708 WP_076388489.1 DUF4433 domain-containing protein -
CZ356_RS09785 578781..579011 + 231 WP_197684215.1 hypothetical protein -
CZ356_RS09735 579352..579627 + 276 WP_173818515.1 hypothetical protein -
CZ356_RS02660 579676..579924 - 249 WP_076388493.1 ribbon-helix-helix domain-containing protein -
CZ356_RS02665 580186..580368 + 183 WP_076388495.1 hypothetical protein -
CZ356_RS02670 580640..581548 - 909 WP_076388497.1 3'-5' exoribonuclease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-112)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 116 a.a.        Molecular weight: 12700.56 Da        Isoelectric Point: 9.1668

>T293448 WP_076388485.1 NZ_LT706985:c576670-576323 [Propionimicrobium sp. Marseille-P3275]
MRRGEIRLVNLDPVVGSESNKLRPCVIVSNNNANDTAELLGRGVVTVVPLTSNTMRVYPFQTLLDSADTGLGEDSKAQAE
QVRSVDVRRIGKKIGQLSMRQQFALDEALRLHLQL

Download         Length: 348 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8547.43 Da        Isoelectric Point: 4.2108

>AT293448 WP_076388487.1 NZ_LT706985:c576896-576657 [Propionimicrobium sp. Marseille-P3275]
MKLSVSLSNSDLELLDRIVSEAGLASRSAGVQLALKSLVDPNLRDAYASAWREWASDSDNLAWDTAVNDGFEELGHAAR

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References