Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 4769861..4770386 Replicon chromosome
Accession NC_021055
Organism Streptomyces sp. PAMC26508

Toxin (Protein)


Gene name relE Uniprot ID A0A4P7DII6
Locus tag F750_RS21315 Protein ID WP_015578584.1
Coordinates 4769861..4770124 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A3N6F7F2
Locus tag F750_RS21320 Protein ID WP_015578585.1
Coordinates 4770117..4770386 (-) Length 90 a.a.

Genomic Context

F750_RS21285F750_RS21295F750_RS21340F750_RS21290F750_RS21300F750_RS21305F750_RS21310F750_RS21315F750_RS21320F750_RS21325F750_RS21330F750_RS21335
Location: 4765814..4766551 (738 bp)
Type: Others
Protein ID: WP_015578580.1
Location: 4767429..4768517 (1089 bp)
Type: Others
Protein ID: WP_014154299.1
Location: 4774686..4775168 (483 bp)
Type: Others
Protein ID: WP_014154291.1
Location: 4766570..4767184 (615 bp)
Type: Others
Protein ID: WP_014154300.1
Location: 4768639..4769031 (393 bp)
Type: Others
Protein ID: WP_015578581.1
Location: 4769031..4769282 (252 bp)
Type: Others
Protein ID: WP_015578582.1
Location: 4769359..4769550 (192 bp)
Type: Others
Protein ID: Protein_4229
Location: 4769861..4770124 (264 bp)
Type: Toxin
Protein ID: WP_015578584.1
Location: 4770117..4770386 (270 bp)
Type: Antitoxin
Protein ID: WP_015578585.1
Location: 4770781..4771467 (687 bp)
Type: Others
Protein ID: WP_041667870.1
Location: 4771451..4771888 (438 bp)
Type: Others
Protein ID: WP_015578588.1
Location: 4771909..4774323 (2415 bp)
Type: Others
Protein ID: WP_015578589.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
F750_RS212854765814..4766551+738WP_015578580.1ROK family protein-
F750_RS212904766570..4767184-615WP_014154300.1hypothetical protein-
F750_RS212954767429..4768517+1089WP_014154299.1redox-regulated ATPase YchF-
F750_RS213004768639..4769031-393WP_015578581.1hypothetical protein-
F750_RS213054769031..4769282-252WP_015578582.1hypothetical protein-
F750_RS213104769359..4769550-192Protein_4229hypothetical protein-
F750_RS213154769861..4770124-264WP_015578584.1type II toxin-antitoxin system RelE/ParE family toxinToxin
F750_RS213204770117..4770386-270WP_015578585.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
F750_RS213254770781..4771467-687WP_041667870.1hypothetical protein-
F750_RS213304771451..4771888-438WP_015578588.1hypothetical protein-
F750_RS213354771909..4774323-2415WP_015578589.1DUF1906 domain-containing protein-
F750_RS213404774686..4775168+483WP_014154291.1cupin domain-containing protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-58)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 9950.52 Da        Isoelectric Point: 10.4269

>T29344 WP_015578584.1 NC_021055:c4770124-4769861 [Streptomyces sp. PAMC 26508]
VSEYRAVFRPEAQAELRKIPREKALRILTKLTELESAPLGFATTALVSQPERRRLRVGDYRVVYTIDKGELVVWVVHVGH
RSTVYGT

Download         Length: 264 bp

>T29344 NC_021055:c4770124-4769861 [Streptomyces sp. PAMC 26508]
GTGAGTGAGTACCGGGCCGTCTTCCGGCCAGAGGCACAGGCCGAGCTCCGGAAGATCCCTCGCGAAAAGGCCCTACGCAT
CCTGACCAAACTGACCGAGCTGGAGAGCGCCCCCCTCGGCTTTGCCACCACCGCGCTCGTGTCACAGCCGGAACGCCGTC
GGCTGCGGGTCGGTGACTACCGCGTCGTCTACACGATCGACAAGGGAGAGCTCGTGGTGTGGGTCGTCCACGTCGGGCAT
CGCTCCACCGTCTACGGCACCTGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10304.81 Da        Isoelectric Point: 4.7473

>AT29344 WP_015578585.1 NC_021055:c4770386-4770117 [Streptomyces sp. PAMC 26508]
MTQPLPIESIRDVRAHLAEVVERADRDDMPTVITRRGKQIAAVVSIEVLRKYQEWEEREINRIIDERMANPAPGIPIEDI
MRETLARGE

Download         Length: 270 bp

>AT29344 NC_021055:c4770386-4770117 [Streptomyces sp. PAMC 26508]
ATGACGCAGCCACTGCCCATAGAGTCCATCCGTGACGTACGTGCACACCTGGCCGAGGTCGTGGAGCGCGCCGATCGAGA
TGACATGCCCACCGTGATCACCCGACGGGGCAAGCAGATTGCCGCTGTCGTCTCCATCGAGGTGCTGCGCAAGTACCAGG
AATGGGAAGAGCGCGAGATCAACCGGATCATCGACGAACGCATGGCCAACCCGGCACCCGGCATCCCGATCGAGGACATC
ATGAGGGAGACGCTGGCGCGCGGTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A4P7DII6

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A3N6F7F2

References