Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1363019..1363499 Replicon chromosome
Accession NZ_LT635480
Organism Ndongobacter massiliensis strain Marseille-P3170T

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BQ7385_RS06610 Protein ID WP_072514801.1
Coordinates 1363019..1363285 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag BQ7385_RS06615 Protein ID WP_072514802.1
Coordinates 1363272..1363499 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BQ7385_RS06595 1359225..1361000 - 1776 WP_072514798.1 aminopeptidase P family protein -
BQ7385_RS06600 1361083..1361616 - 534 WP_072514799.1 methylated-DNA--[protein]-cysteine S-methyltransferase -
BQ7385_RS06605 1361859..1362962 + 1104 WP_072514800.1 redox-regulated ATPase YchF -
BQ7385_RS06610 1363019..1363285 - 267 WP_072514801.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BQ7385_RS06615 1363272..1363499 - 228 WP_072514802.1 antitoxin Antitoxin
BQ7385_RS06620 1363590..1365014 - 1425 WP_072514803.1 FHA domain-containing protein -
BQ7385_RS06625 1365016..1365591 - 576 WP_072514804.1 prepilin peptidase -
BQ7385_RS06630 1365596..1366891 - 1296 WP_072514805.1 CpaF family protein -
BQ7385_RS06635 1366873..1367976 - 1104 WP_072514806.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1302447..1450264 147817


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-88)

Antitoxin

Protein of unknown function DUF6290

(1-71)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10598.35 Da        Isoelectric Point: 10.8167

>T293414 WP_072514801.1 NZ_LT635480:c1363285-1363019 [Ndongobacter massiliensis]
MKKYEIELTERFKKDFRKLDRYTQKIIRAWMNKNLVACENPRQHGKGLTANRSGQWRYRIGSYRLIATIDDNKLIILALS
VGHRREIY

Download         Length: 267 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8765.69 Da        Isoelectric Point: 4.0466

>AT293414 WP_072514802.1 NZ_LT635480:c1363499-1363272 [Ndongobacter massiliensis]
MAFSIRLTEEERKLATAYARLHGVSVGEAFKQALFERIEDEYDLAVAEEAYREYLESGCQSTPIEEFWRELDEEV

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References