Detailed information of TA system TA293414

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 1363019..1363499
• Replicon: chromosome
• Accession: NZ_LT635480
• Organism: Ndongobacter massiliensis strain Marseille-P3170T

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: BQ7385_RS06610
• Protein ID: WP_072514801.1
• Coordinates: 1363019..1363285 (-)
• Length: 89 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: BQ7385_RS06615
• Protein ID: WP_072514802.1
• Coordinates: 1363272..1363499 (-)
• Length: 76 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BQ7385_RS06595	1359225..1361000	-	1776	WP_072514798.1	aminopeptidase P family protein	-
BQ7385_RS06600	1361083..1361616	-	534	WP_072514799.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
BQ7385_RS06605	1361859..1362962	+	1104	WP_072514800.1	redox-regulated ATPase YchF	-
BQ7385_RS06610	1363019..1363285	-	267	WP_072514801.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BQ7385_RS06615	1363272..1363499	-	228	WP_072514802.1	antitoxin	Antitoxin
BQ7385_RS06620	1363590..1365014	-	1425	WP_072514803.1	FHA domain-containing protein	-
BQ7385_RS06625	1365016..1365591	-	576	WP_072514804.1	prepilin peptidase	-
BQ7385_RS06630	1365596..1366891	-	1296	WP_072514805.1	CpaF family protein	-
BQ7385_RS06635	1366873..1367976	-	1104	WP_072514806.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	-	1302447..1450264	147817

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-88)

Antitoxin

• Protein of unknown function DUF6290 (1-71)

Sequences

Toxin

Protein

• Length: 89 a.a.
• Molecular weight: 10598.35 Da
• Isoelectric Point: 10.8167

>T293414 WP_072514801.1 NZ_LT635480:c1363285-1363019 [Ndongobacter massiliensis]
MKKYEIELTERFKKDFRKLDRYTQKIIRAWMNKNLVACENPRQHGKGLTANRSGQWRYRIGSYRLIATIDDNKLIILALS
VGHRREIY

Nucleotide

• Length: 267 bp

Antitoxin

Protein

• Length: 76 a.a.
• Molecular weight: 8765.69 Da
• Isoelectric Point: 4.0466

>AT293414 WP_072514802.1 NZ_LT635480:c1363499-1363272 [Ndongobacter massiliensis]
MAFSIRLTEEERKLATAYARLHGVSVGEAFKQALFERIEDEYDLAVAEEAYREYLESGCQSTPIEEFWRELDEEV

Nucleotide

• Length: 228 bp