Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 1267677..1268209 Replicon chromosome
Accession NZ_LT635457
Organism Actinomyces pacaensis strain Marseille-P2985T

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag BQ7111_RS05545 Protein ID WP_072456903.1
Coordinates 1267943..1268209 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag BQ7111_RS05540 Protein ID WP_072456901.1
Coordinates 1267677..1267940 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BQ7111_RS05520 1263061..1263486 + 426 WP_072456892.1 YjdF family protein -
BQ7111_RS05525 1263715..1264809 + 1095 WP_072456894.1 DUF1266 domain-containing protein -
BQ7111_RS05530 1265043..1265375 + 333 WP_072456896.1 DsrE family protein -
BQ7111_RS05535 1265832..1267538 + 1707 WP_072456898.1 ATP-binding cassette domain-containing protein -
BQ7111_RS05540 1267677..1267940 + 264 WP_072456901.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
BQ7111_RS05545 1267943..1268209 + 267 WP_072456903.1 Txe/YoeB family addiction module toxin Toxin
BQ7111_RS05550 1268221..1269714 - 1494 WP_072456905.1 cardiolipin synthase -
BQ7111_RS05555 1269720..1271297 - 1578 WP_072456909.1 methyltransferase -
BQ7111_RS05560 1271444..1272409 + 966 WP_072456912.1 DUF808 domain-containing protein -
BQ7111_RS05565 1272537..1273133 + 597 WP_019126796.1 superoxide dismutase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10795.09 Da        Isoelectric Point: 7.2739

>T293412 WP_072456903.1 NZ_LT635457:1267943-1268209 [Actinomyces pacaensis]
MHITWDEEAWNDYVWWQFEDRKTLKRINALIKDIQSNGNEGIGKPEPLRYEFSGYWSRRIDSRHRLIYQISDDGKTLWII
SCRYHYGQ

Download         Length: 267 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 10004.16 Da        Isoelectric Point: 4.4630

>AT293412 WP_072456901.1 NZ_LT635457:1267677-1267940 [Actinomyces pacaensis]
MKTMTYSESRARYAEVLDQVVNDREEIIITRQGHESAVIMALDEYESLMETVYLMQSPANARHLRESIARHRAGEGVVHD
LVEPDED

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References