Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) abiEi-abiEii/AbiEi(antitoxin)
Location 206817..207639 Replicon chromosome
Accession NZ_LT632322
Organism Murdochiella vaginalis strain Marseille-P2341T

Toxin (Protein)


Gene name abiEi Uniprot ID -
Locus tag BN8034_RS07890 Protein ID WP_071704944.1
Coordinates 207445..207639 (+) Length 65 a.a.

Antitoxin (Protein)


Gene name abiEii Uniprot ID -
Locus tag BN8034_RS00850 Protein ID WP_071704943.1
Coordinates 206817..207452 (+) Length 212 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BN8034_RS00835 201912..203300 - 1389 WP_071704941.1 FAD-dependent oxidoreductase -
BN8034_RS07765 203594..203764 - 171 WP_157885016.1 hypothetical protein -
BN8034_RS00840 204057..205067 + 1011 WP_071704942.1 LacI family transcriptional regulator -
BN8034_RS07610 205080..206747 + 1668 WP_083428128.1 hypothetical protein -
BN8034_RS00850 206817..207452 + 636 WP_071704943.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
BN8034_RS07890 207445..207639 + 195 WP_071704944.1 hypothetical protein Toxin
BN8034_RS00860 208007..210751 + 2745 WP_071704945.1 cation-translocating P-type ATPase -
BN8034_RS00865 210831..211328 + 498 WP_071704946.1 5-(carboxyamino)imidazole ribonucleotide mutase -
BN8034_RS00870 211456..212172 + 717 WP_071704947.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

(21-67)


Sequences


Toxin        


Download         Length: 65 a.a.        Molecular weight: 7323.61 Da        Isoelectric Point: 6.9724

>T293401 WP_071704944.1 NZ_LT632322:207445-207639 [Murdochiella vaginalis]
MNKANVLALCHKVEQKTGLSFNTVLLYYFLESILKRLTDGENKDSFRQMVSLDIAMVDVITPLF

Download         Length: 195 bp


Antitoxin


Download         Length: 212 a.a.        Molecular weight: 24415.95 Da        Isoelectric Point: 9.5356

>AT293401 WP_071704943.1 NZ_LT632322:206817-207452 [Murdochiella vaginalis]
MVLFPCDNNKRRKKSNYQSKIESYLQKNNGLISSSYCKSRGIPTVYLTRLHRRGKLLRLTKGLYGLPDGGYDELFVFQHR
YKSTIFSYETALFLLGESDRIPQSIDVTVANSYKFNEPPANLLIHYVDPKIISLGVQSVQTMFGNSVKAYSYERVLCDFI
ANKDKVDAESYVKTIQGYAKYQNRDVHHLWEIAHALGIENRVRNILELIYE

Download         Length: 636 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References