Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | abiEi-abiEii/AbiEi(antitoxin) |
Location | 206817..207639 | Replicon | chromosome |
Accession | NZ_LT632322 | ||
Organism | Murdochiella vaginalis strain Marseille-P2341T |
Toxin (Protein)
Gene name | abiEi | Uniprot ID | - |
Locus tag | BN8034_RS07890 | Protein ID | WP_071704944.1 |
Coordinates | 207445..207639 (+) | Length | 65 a.a. |
Antitoxin (Protein)
Gene name | abiEii | Uniprot ID | - |
Locus tag | BN8034_RS00850 | Protein ID | WP_071704943.1 |
Coordinates | 206817..207452 (+) | Length | 212 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BN8034_RS00835 | 201912..203300 | - | 1389 | WP_071704941.1 | FAD-dependent oxidoreductase | - |
BN8034_RS07765 | 203594..203764 | - | 171 | WP_157885016.1 | hypothetical protein | - |
BN8034_RS00840 | 204057..205067 | + | 1011 | WP_071704942.1 | LacI family transcriptional regulator | - |
BN8034_RS07610 | 205080..206747 | + | 1668 | WP_083428128.1 | hypothetical protein | - |
BN8034_RS00850 | 206817..207452 | + | 636 | WP_071704943.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
BN8034_RS07890 | 207445..207639 | + | 195 | WP_071704944.1 | hypothetical protein | Toxin |
BN8034_RS00860 | 208007..210751 | + | 2745 | WP_071704945.1 | cation-translocating P-type ATPase | - |
BN8034_RS00865 | 210831..211328 | + | 498 | WP_071704946.1 | 5-(carboxyamino)imidazole ribonucleotide mutase | - |
BN8034_RS00870 | 211456..212172 | + | 717 | WP_071704947.1 | phosphoribosylaminoimidazolesuccinocarboxamide synthase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 65 a.a. Molecular weight: 7323.61 Da Isoelectric Point: 6.9724
>T293401 WP_071704944.1 NZ_LT632322:207445-207639 [Murdochiella vaginalis]
MNKANVLALCHKVEQKTGLSFNTVLLYYFLESILKRLTDGENKDSFRQMVSLDIAMVDVITPLF
MNKANVLALCHKVEQKTGLSFNTVLLYYFLESILKRLTDGENKDSFRQMVSLDIAMVDVITPLF
Download Length: 195 bp
Antitoxin
Download Length: 212 a.a. Molecular weight: 24415.95 Da Isoelectric Point: 9.5356
>AT293401 WP_071704943.1 NZ_LT632322:206817-207452 [Murdochiella vaginalis]
MVLFPCDNNKRRKKSNYQSKIESYLQKNNGLISSSYCKSRGIPTVYLTRLHRRGKLLRLTKGLYGLPDGGYDELFVFQHR
YKSTIFSYETALFLLGESDRIPQSIDVTVANSYKFNEPPANLLIHYVDPKIISLGVQSVQTMFGNSVKAYSYERVLCDFI
ANKDKVDAESYVKTIQGYAKYQNRDVHHLWEIAHALGIENRVRNILELIYE
MVLFPCDNNKRRKKSNYQSKIESYLQKNNGLISSSYCKSRGIPTVYLTRLHRRGKLLRLTKGLYGLPDGGYDELFVFQHR
YKSTIFSYETALFLLGESDRIPQSIDVTVANSYKFNEPPANLLIHYVDPKIISLGVQSVQTMFGNSVKAYSYERVLCDFI
ANKDKVDAESYVKTIQGYAKYQNRDVHHLWEIAHALGIENRVRNILELIYE
Download Length: 636 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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