Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-MazE
Location 2639884..2640473 Replicon chromosome
Accession NZ_LT630450
Organism Desulfovibrio piger strain FI11049 isolate FI11049

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag DESPIGER_RS11750 Protein ID WP_072337186.1
Coordinates 2640141..2640473 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag DESPIGER_RS11745 Protein ID WP_072337184.1
Coordinates 2639884..2640141 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DESPIGER_RS12715 2638771..2638944 - 174 WP_083575400.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
DESPIGER_RS11740 2639040..2639795 - 756 WP_156831704.1 hypothetical protein -
DESPIGER_RS11745 2639884..2640141 + 258 WP_072337184.1 antitoxin Antitoxin
DESPIGER_RS11750 2640141..2640473 + 333 WP_072337186.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
DESPIGER_RS11755 2640490..2642265 - 1776 WP_072337187.1 TraM recognition domain-containing protein -
DESPIGER_RS11760 2642273..2643592 - 1320 WP_072337189.1 hypothetical protein -
DESPIGER_RS11765 2643589..2644101 - 513 WP_083575402.1 lytic transglycosylase domain-containing protein -
DESPIGER_RS11770 2644098..2644514 - 417 WP_072337191.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 2627314..2666834 39520


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-109)

Antitoxin

Antitoxin PemI-like

(5-83)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 11989.78 Da        Isoelectric Point: 8.5532

>T293399 WP_072337186.1 NZ_LT630450:2640141-2640473 [Desulfovibrio piger]
MRRGDIYLVTLDPTEGHEQQGTRPVLVISPDEFNRVTQVPVVLPITSGGNFARTAGFAVSLSGCGTRTTGVIRCDQPRAL
DLRARSGRRLEQVPPVIMDEVLARLATIFS

Download         Length: 333 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9024.43 Da        Isoelectric Point: 4.6280

>AT293399 WP_072337184.1 NZ_LT630450:2639884-2640141 [Desulfovibrio piger]
MYTANLRKVGGSVMLAVPPAILEMLQMESGSSVSMAVESGRLIIEPNVRKKYSLQELLAQCDPSAPLSSEDGVWTGSGAT
GRELI

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References