Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 813078..813595 Replicon chromosome
Accession NZ_LT630450
Organism Desulfovibrio piger strain FI11049 isolate FI11049

Toxin (Protein)


Gene name relE Uniprot ID A0A1K1LD51
Locus tag DESPIGER_RS03995 Protein ID WP_072333371.1
Coordinates 813078..813338 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A1K1LDA5
Locus tag DESPIGER_RS04000 Protein ID WP_072333374.1
Coordinates 813341..813595 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DESPIGER_RS03970 808107..808646 + 540 WP_072333356.1 hypothetical protein -
DESPIGER_RS03975 808643..809305 + 663 WP_072333359.1 hypothetical protein -
DESPIGER_RS03980 809318..810100 + 783 WP_072333362.1 hypothetical protein -
DESPIGER_RS03985 810110..811660 + 1551 WP_072333365.1 hypothetical protein -
DESPIGER_RS03990 812164..812928 - 765 WP_072333368.1 endonuclease -
DESPIGER_RS03995 813078..813338 - 261 WP_072333371.1 Txe/YoeB family addiction module toxin Toxin
DESPIGER_RS04000 813341..813595 - 255 WP_072333374.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-69)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10376.93 Da        Isoelectric Point: 8.4776

>T293397 WP_072333371.1 NZ_LT630450:c813338-813078 [Desulfovibrio piger]
MLLTWTSQAWEDYLYWQATDKRTVKRINELLRDALRNPFEGLGKPEPLRFDLAGCWSRRINQEDRLVYRLDAQGMALIVL
QCRYHY

Download         Length: 261 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9440.66 Da        Isoelectric Point: 5.5169

>AT293397 WP_072333374.1 NZ_LT630450:c813595-813341 [Desulfovibrio piger]
MSQAITYTEARQNLAETMNRVCDHHEPVIITRQKSPSVVMMSLEDYNAIMETAYLLRSPANAARLREALHAADAGKTVQH
DLED

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1K1LD51

Antitoxin

Source ID Structure
AlphaFold DB A0A1K1LDA5

References