Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09907-MazE
Location 2497320..2497921 Replicon chromosome
Accession NZ_LT630287
Organism Ligilactobacillus acidipiscis strain ACA-DC 1533

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag BQ5903_RS11585 Protein ID WP_056972590.1
Coordinates 2497320..2497664 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag BQ5903_RS11590 Protein ID WP_056972592.1
Coordinates 2497658..2497921 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BQ5903_RS11565 2492564..2494258 + 1695 WP_079579603.1 aryl-sulfate sulfotransferase -
BQ5903_RS11570 2494417..2495124 + 708 WP_010495907.1 glucosamine-6-phosphate deaminase -
BQ5903_RS11575 2495729..2496622 - 894 WP_079578748.1 IS982 family transposase -
BQ5903_RS11580 2496730..2497176 + 447 Protein_2231 helicase -
BQ5903_RS11585 2497320..2497664 - 345 WP_056972590.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
BQ5903_RS11590 2497658..2497921 - 264 WP_056972592.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
BQ5903_RS11595 2498017..2498604 + 588 WP_079579604.1 site-specific integrase -
BQ5903_RS11600 2498617..2498976 + 360 WP_056972596.1 hypothetical protein -
BQ5903_RS11605 2499102..2500487 - 1386 WP_079579685.1 group II intron reverse transcriptase/maturase -
BQ5903_RS11610 2500987..2502117 - 1131 WP_079579605.1 NAD(P)-dependent alcohol dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-104)

Antitoxin

Antitoxin PemI-like

(8-85)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13111.00 Da        Isoelectric Point: 6.8698

>T293395 WP_056972590.1 NZ_LT630287:c2497664-2497320 [Ligilactobacillus acidipiscis]
MVSQGDIFYVNFNPRRGHEQMNKRPAIALSNDLVCQTSNMTIVAPISSTKRNFPMYHRLTSSQTVYGKVLLDQTIALDLR
ARHVTDETIVDHVSREELEEIITLYKLLFSIDDK

Download         Length: 345 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 10140.48 Da        Isoelectric Point: 6.4690

>AT293395 WP_056972592.1 NZ_LT630287:c2497921-2497658 [Ligilactobacillus acidipiscis]
MELIKEQTRLAKWGNSKAARIPSQIIKQLKLDDNQDMTITIENGSIVLTPIKKNPTNIHELFKNWQDDGKRDHELDWGKS
EGNELQW

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References