Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | yafW-ykfI/CbtA-CbeA |
Location | 262720..263399 | Replicon | chromosome |
Accession | NZ_LT615378 | ||
Organism | Escherichia coli isolate 103 |
Toxin (Protein)
Gene name | ykfI | Uniprot ID | P77692 |
Locus tag | BV310_RS01320 | Protein ID | WP_000854672.1 |
Coordinates | 262720..263061 (-) | Length | 114 a.a. |
Antitoxin (Protein)
Gene name | yafW | Uniprot ID | Q47684 |
Locus tag | BV310_RS01325 | Protein ID | WP_000070395.1 |
Coordinates | 263082..263399 (-) | Length | 106 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BV310_RS01295 | 257997..258398 | + | 402 | WP_000174689.1 | sigma factor-binding protein Crl | - |
BV310_RS01300 | 258437..259492 | - | 1056 | WP_000749863.1 | phosphoporin PhoE | - |
BV310_RS01305 | 259780..260883 | + | 1104 | WP_001285288.1 | glutamate 5-kinase | - |
BV310_RS01310 | 260895..262148 | + | 1254 | WP_000893278.1 | glutamate-5-semialdehyde dehydrogenase | - |
BV310_RS01320 | 262720..263061 | - | 342 | WP_000854672.1 | type IV toxin-antitoxin system toxin YkfI | Toxin |
BV310_RS01325 | 263082..263399 | - | 318 | WP_000070395.1 | type IV toxin-antitoxin system antitoxin YafW | Antitoxin |
BV310_RS01330 | 263418..263639 | - | 222 | WP_000691994.1 | DUF987 domain-containing protein | - |
BV310_RS01335 | 263648..264124 | - | 477 | WP_000811693.1 | RadC family protein | - |
BV310_RS01340 | 264140..264598 | - | 459 | WP_000211838.1 | antirestriction protein | - |
BV310_RS01345 | 264696..264935 | - | 240 | WP_000194654.1 | DUF905 domain-containing protein | - |
BV310_RS01350 | 265012..265479 | - | 468 | WP_001547765.1 | hypothetical protein | - |
BV310_RS24920 | 265502..265945 | - | 444 | WP_000824223.1 | hypothetical protein | - |
BV310_RS24925 | 265945..266172 | - | 228 | WP_001548158.1 | hypothetical protein | - |
BV310_RS24930 | 266168..266359 | - | 192 | Protein_250 | DeoR family transcriptional regulator | - |
BV310_RS01365 | 266576..267397 | - | 822 | WP_000197389.1 | DUF945 domain-containing protein | - |
BV310_RS01370 | 267489..268352 | - | 864 | WP_001065553.1 | GTPase family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 114 a.a. Molecular weight: 12905.01 Da Isoelectric Point: 9.6543
>T293366 WP_000854672.1 NZ_LT615378:c263061-262720 [Escherichia coli]
MKTLPAITQRAVKPCLSPVAVWQMLLTRLLEQHYGLTINDTPFCNEAVIKEHIDAGITLADAVNFLVEKYELVRIDRKGF
SWQEQSPYLRAADILRARQATGLLRQSRNNVVR
MKTLPAITQRAVKPCLSPVAVWQMLLTRLLEQHYGLTINDTPFCNEAVIKEHIDAGITLADAVNFLVEKYELVRIDRKGF
SWQEQSPYLRAADILRARQATGLLRQSRNNVVR
Download Length: 342 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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