Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 3365364..3366148 Replicon chromosome
Accession NZ_LT615367
Organism Dickeya aquatica strain 174/2

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag DAQ1742_RS15345 Protein ID WP_071604060.1
Coordinates 3365364..3365858 (-) Length 165 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID A0A375ADW5
Locus tag DAQ1742_RS15350 Protein ID WP_035340289.1
Coordinates 3365855..3366148 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DAQ1742_RS15330 3361713..3363866 - 2154 WP_067486626.1 ornithine decarboxylase -
DAQ1742_RS15340 3364649..3365266 + 618 Protein_2986 IS256 family transposase -
DAQ1742_RS15345 3365364..3365858 - 495 WP_071604060.1 GNAT family N-acetyltransferase Toxin
DAQ1742_RS15350 3365855..3366148 - 294 WP_035340289.1 DUF1778 domain-containing protein Antitoxin
DAQ1742_RS15355 3367616..3368281 + 666 WP_035340287.1 HAD-IB family hydrolase -
DAQ1742_RS15360 3368642..3369217 - 576 WP_035340285.1 TerD family protein -
DAQ1742_RS15365 3369303..3369881 - 579 WP_035340283.1 TerD family protein -
DAQ1742_RS15370 3369934..3370977 - 1044 WP_035340281.1 TerC/Alx family metal homeostasis membrane protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(76-143)

Antitoxin

Vibrio phage ICP1, Orf50

(14-88)


Sequences

Toxin        


Download         Length: 165 a.a.        Molecular weight: 17620.53 Da        Isoelectric Point: 7.8046

>T293332 WP_071604060.1 NZ_LT615367:c3365858-3365364 [Dickeya aquatica]
MISAPEPLHAEHVLSSFCCGVESMDNWLKLRAMKNQVTGASRTFVSCDGSKVLAYYSLASSAVATNVAPGRFRRNMPDPI
PVVVLGRLAVDKSLHGQGVGRALVRDAGLRVIQVADTIGIRGMLVHALSDEAREFYLRVGFEPSPIDPMILMVTLGDLVG
SLSI

Download         Length: 495 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10886.47 Da        Isoelectric Point: 10.1968

>AT293332 WP_035340289.1 NZ_LT615367:c3366148-3365855 [Dickeya aquatica]
MPATNSVSVKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIDQRIVMADPDAYQEFLVRLDQAPSPN
AALRKTMQTPAPWEQKK

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A375ADW5

References