Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 3153273..3153897 Replicon chromosome
Accession NZ_LT615367
Organism Dickeya aquatica strain 174/2

Toxin (Protein)


Gene name Hha Uniprot ID E0SD87
Locus tag DAQ1742_RS14245 Protein ID WP_009114000.1
Coordinates 3153694..3153897 (+) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID -
Locus tag DAQ1742_RS14240 Protein ID WP_035340556.1
Coordinates 3153273..3153641 (+) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DAQ1742_RS14225 3149066..3152218 + 3153 WP_035340560.1 multidrug efflux RND transporter permease subunit -
DAQ1742_RS14230 3152379..3152630 + 252 WP_035340558.1 type B 50S ribosomal protein L31 -
DAQ1742_RS14235 3152646..3152789 + 144 WP_071604062.1 type B 50S ribosomal protein L36 -
DAQ1742_RS14240 3153273..3153641 + 369 WP_035340556.1 Hha toxicity modulator TomB Antitoxin
DAQ1742_RS14245 3153694..3153897 + 204 WP_009114000.1 hemolysin expression modulator Hha Toxin
DAQ1742_RS14255 3154568..3154891 + 324 WP_035345804.1 MGMT family protein -
DAQ1742_RS14260 3154949..3155509 - 561 WP_035340554.1 YbaY family lipoprotein -
DAQ1742_RS14265 3155755..3156618 + 864 WP_035340553.1 acyl-CoA thioesterase II -
DAQ1742_RS14270 3156775..3158067 - 1293 WP_035340550.1 ammonium transporter AmtB -
DAQ1742_RS14275 3158111..3158449 - 339 WP_002208627.1 P-II family nitrogen regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-118)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8133.51 Da        Isoelectric Point: 8.8500

>T293331 WP_009114000.1 NZ_LT615367:3153694-3153897 [Dickeya aquatica]
MKKIDYLMRLRKCTTIDTLERVIEKNKYELSNDELEMFYSAADHRLAELTMNKLYDKVPTAVWKYVR

Download         Length: 204 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14209.98 Da        Isoelectric Point: 4.9037

>AT293331 WP_035340556.1 NZ_LT615367:3153273-3153641 [Dickeya aquatica]
MDEYTPQHYDIAQLRFLCENLHDESIATLGDSSHGWVNDPTSAVNLQLNELIEHIAAFVVTYKIKYPHESGLCERVEKYL
DDTYILFSNYGINDTELQKWQKSKSQLFRMFSEKNVCTVVKT

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1X3RNQ0

Antitoxin

Source ID Structure

References