Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 1498816..1499369 Replicon chromosome
Accession NZ_LT615367
Organism Dickeya aquatica strain 174/2

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag DAQ1742_RS06670 Protein ID WP_035342967.1
Coordinates 1498816..1499130 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID A0A375A8K7
Locus tag DAQ1742_RS06675 Protein ID WP_035342965.1
Coordinates 1499133..1499369 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DAQ1742_RS06660 1497808..1498023 - 216 Protein_1279 transposase -
DAQ1742_RS06665 1498195..1498491 - 297 WP_067487160.1 hypothetical protein -
DAQ1742_RS06670 1498816..1499130 - 315 WP_035342967.1 CcdB family protein Toxin
DAQ1742_RS06675 1499133..1499369 - 237 WP_035342965.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
DAQ1742_RS06680 1499730..1500296 - 567 WP_180706259.1 DDE-type integrase/transposase/recombinase -
DAQ1742_RS06685 1500257..1500652 - 396 WP_145916196.1 transposase -
DAQ1742_RS06690 1500733..1501865 + 1133 WP_145916195.1 IS3 family transposase -
DAQ1742_RS06695 1501883..1502764 - 882 Protein_1286 integrase arm-type DNA-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-103)

Antitoxin

Post-segregation antitoxin CcdA

(9-78)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11493.40 Da        Isoelectric Point: 7.9859

>T293326 WP_035342967.1 NZ_LT615367:c1499130-1498816 [Dickeya aquatica]
MQFTVYGNTGKSAVYPLLLDVTSDIIGQLNRRIVIPLLPVEKYPAGRRPDRLVPVVRLTDGKEYAVMTHELASIPVQALG
AVFCDASQYRTQVKAAIDFLIDGF

Download         Length: 315 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 9034.09 Da        Isoelectric Point: 6.7184

>AT293326 WP_035342965.1 NZ_LT615367:c1499369-1499133 [Dickeya aquatica]
MTAKQRNTQSVTMTVERALLLRAREAGINLSATLTAALDAELRRHEAKKWQEENREAIDALNRFHDEHGCFSDEYRTF

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A375A8K7

References