Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 741293..741971 Replicon chromosome
Accession NZ_LT615367
Organism Dickeya aquatica strain 174/2

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag DAQ1742_RS03400 Protein ID WP_035339869.1
Coordinates 741540..741971 (+) Length 144 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A375A716
Locus tag DAQ1742_RS03395 Protein ID WP_035339867.1
Coordinates 741293..741559 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DAQ1742_RS03375 737713..738354 + 642 WP_035339858.1 LysE family translocator -
DAQ1742_RS03380 738426..739034 - 609 WP_035339860.1 HD domain-containing protein -
DAQ1742_RS03385 739241..739891 + 651 WP_035339863.1 hemolysin III family protein -
DAQ1742_RS03390 739994..740974 - 981 WP_035339865.1 tRNA-modifying protein YgfZ -
DAQ1742_RS03395 741293..741559 + 267 WP_035339867.1 FAD assembly factor SdhE Antitoxin
DAQ1742_RS03400 741540..741971 + 432 WP_035339869.1 protein YgfX Toxin
DAQ1742_RS03405 742038..742556 - 519 WP_035339871.1 flavodoxin FldB -
DAQ1742_RS03410 742664..743989 - 1326 WP_035345729.1 MHS family MFS transporter -
DAQ1742_RS03415 744252..745151 + 900 WP_035339873.1 site-specific tyrosine recombinase XerD -
DAQ1742_RS03420 745240..745971 + 732 WP_035339875.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-131)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 144 a.a.        Molecular weight: 16693.63 Da        Isoelectric Point: 12.0401

>T293325 WP_035339869.1 NZ_LT615367:741540-741971 [Dickeya aquatica]
VALWQCDLRVSWRMQLFSLMMHGLLVLMILLAPWPDGYAPLWLGLVTLVVFGFVRSQRVIKSRQGEISLHDENRLHWQQR
DWLIVRRPWMLRSGILLSLRAANGKGRQHLWLASDSMGNAEWRRLRQLLQHPALSGAESSRHP

Download         Length: 432 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10459.95 Da        Isoelectric Point: 5.1137

>AT293325 WP_035339867.1 NZ_LT615367:741293-741559 [Dickeya aquatica]
MDIDNKSRIHWACRRGMRELDISIMPFFEHEYDALSDDDKHQFIRLLECDDPDLFNWLMNHGEPVDPGLKRMVSLIQTRN
KDRGLVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A375A716

References