Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PanAT/DUF4065(antitoxin)
Location 278606..279531 Replicon chromosome
Accession NZ_LT608330
Organism Pseudomonas aeruginosa isolate PA14Or_reads

Toxin (Protein)


Gene name panT Uniprot ID -
Locus tag PHAGEPCYII10_RS01270 Protein ID WP_170868735.1
Coordinates 279205..279531 (+) Length 109 a.a.

Antitoxin (Protein)


Gene name panA Uniprot ID -
Locus tag PHAGEPCYII10_RS01265 Protein ID WP_003111464.1
Coordinates 278606..279133 (+) Length 176 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PHAGEPCYII10_RS01240 273633..273920 - 288 WP_003137130.1 hypothetical protein -
PHAGEPCYII10_RS01245 274012..274488 - 477 WP_003118626.1 MarR family transcriptional regulator -
PHAGEPCYII10_RS01250 274529..276019 - 1491 WP_003137133.1 UbiD family decarboxylase -
PHAGEPCYII10_RS01255 276153..276839 - 687 WP_003106170.1 DUF1275 domain-containing protein -
PHAGEPCYII10_RS01260 277003..277935 - 933 WP_003084116.1 hypothetical protein -
PHAGEPCYII10_RS01265 278606..279133 + 528 WP_003111464.1 SocA family protein Antitoxin
PHAGEPCYII10_RS01270 279205..279531 + 327 WP_170868735.1 hypothetical protein Toxin
PHAGEPCYII10_RS29975 280973..282415 - 1443 WP_003133043.1 DUF2875 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin SocA-like, Panacea domain

(18-128)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 12385.38 Da        Isoelectric Point: 9.1081

>T293301 WP_170868735.1 NZ_LT608330:279205-279531 [Pseudomonas aeruginosa]
MNDPVYCPVLGYDAVLLVNISTVYPDKYFDQSCILKKGCHPFVLRDSWVVYREAGPFNLARLEQGVAQKSIKTHQPINAG
DFTRIRAGFDISPDVKIKVERFMRQHKI

Download         Length: 327 bp

Antitoxin


Download         Length: 176 a.a.        Molecular weight: 20237.82 Da        Isoelectric Point: 5.7215

>AT293301 WP_003111464.1 NZ_LT608330:278606-279133 [Pseudomonas aeruginosa]
MAAFFLASAEGPLPHLTLIKLLYLADRESMARFDVPMSDDRAVSMPHGPVLSSTLDLIKGRLRSEVWSAWISPLVDHEVR
LVHDVENWDDLDELSRSDRSILESVWQEFGHMTKYQLRDYTHHHIGEWHDPHGSSRDIDPKDTFMALGQSEELAEIKARD
LAERRRHGRKLSEFI

Download         Length: 528 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References