Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1068063..1068709 Replicon chromosome
Accession NZ_LT606949
Organism Polynucleobacter necessarius isolate PPGSP7

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag DXE35_RS05825 Protein ID WP_114689857.1
Coordinates 1068063..1068476 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag DXE35_RS05830 Protein ID WP_114689858.1
Coordinates 1068476..1068709 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DXE35_RS05810 1064014..1064697 - 684 WP_114689854.1 outer membrane lipoprotein carrier protein LolA -
DXE35_RS05815 1064704..1066941 - 2238 WP_197714057.1 DNA translocase FtsK -
DXE35_RS05820 1067055..1068011 + 957 WP_114689856.1 thioredoxin-disulfide reductase -
DXE35_RS05825 1068063..1068476 - 414 WP_114689857.1 tRNA(fMet)-specific endonuclease VapC Toxin
DXE35_RS05830 1068476..1068709 - 234 WP_114689858.1 antitoxin Antitoxin
DXE35_RS05835 1069049..1070895 - 1847 Protein_1174 sodium-translocating pyrophosphatase -
DXE35_RS05840 1071081..1071617 + 537 WP_114689859.1 inorganic diphosphatase -
DXE35_RS05845 1071653..1073272 + 1620 Protein_1176 NAD+ synthase -
DXE35_RS05850 1073345..1073683 + 339 WP_114689860.1 P-II family nitrogen regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-122)

Antitoxin

SpoVT-AbrB domain

(7-50)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15330.73 Da        Isoelectric Point: 7.5189

>T293297 WP_114689857.1 NZ_LT606949:c1068476-1068063 [Polynucleobacter necessarius]
VLKYLLDTNIVIYVIKRKPLEALKVFNKNANRMAISAITLAELIYDAEKSAHVDKNLNVIEDFVSHLEGLPYDINATQHY
GQIKAFLERAGQPIGINDIHIAAHARSHGLTLVTNNMSEFKRVLNLALENWVAASLP

Download         Length: 414 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8927.17 Da        Isoelectric Point: 10.7342

>AT293297 WP_114689858.1 NZ_LT606949:c1068709-1068476 [Polynucleobacter necessarius]
MAISTVFTNNRTQAVRLPAEMRFPENVRKVNVRSKGRERIIAPIENMWDNFFLTAEGVSEDFMNKRGSQEQGDRKPL

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References