Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1057191..1057462 Replicon chromosome
Accession NZ_LT601384
Organism Escherichia coli isolate NCTC86EC

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1057321..1057424 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1057191..1057462 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NCTC86EC_RS04970 1053746..1054408 - 663 WP_000944256.1 exodeoxyribonuclease X -
NCTC86EC_RS04975 1054432..1055088 - 657 WP_066009212.1 carbon-nitrogen hydrolase family protein -
NCTC86EC_RS04980 1055190..1055420 - 231 WP_000916763.1 DNA polymerase III subunit theta -
NCTC86EC_RS04985 1055559..1055933 + 375 WP_000168747.1 CopC domain-containing protein YobA -
NCTC86EC_RS04990 1055937..1056809 + 873 WP_066009214.1 copper homeostasis membrane protein CopD -
NCTC86EC_RS04995 1056822..1057163 + 342 WP_000976476.1 YebY family protein -
- 1057191..1057462 - 272 - - Antitoxin
- 1057321..1057424 + 104 - - Toxin
NCTC86EC_RS05005 1057559..1058215 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
NCTC86EC_RS05010 1058216..1058407 - 192 WP_000457842.1 YebW family protein -
NCTC86EC_RS05015 1058512..1058748 - 237 WP_001295499.1 DUF1480 family protein -
NCTC86EC_RS05020 1058866..1060305 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T293261 NZ_LT601384:1057321-1057424 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT293261 NZ_LT601384:c1057462-1057191 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References