Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 3267301..3267929 Replicon draft genome
Accession NC_021009
Organism Coprococcus catus GD/7

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CC1_RS15450 Protein ID WP_015515296.1
Coordinates 3267528..3267929 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CC1_RS15445 Protein ID WP_015515295.1
Coordinates 3267301..3267531 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CC1_RS15415 (CC1_32260) 3263638..3264192 - 555 WP_015515288.1 GNAT family N-acetyltransferase -
CC1_RS15420 (CC1_32270) 3264368..3265129 + 762 WP_015515289.1 EFR1 family ferrodoxin -
CC1_RS15425 (CC1_32280) 3265129..3265824 + 696 WP_015515290.1 alpha/beta hydrolase -
CC1_RS15430 (CC1_32300) 3265936..3266151 + 216 WP_015515292.1 hypothetical protein -
CC1_RS15435 (CC1_32310) 3266340..3266666 + 327 WP_015515293.1 PadR family transcriptional regulator -
CC1_RS15440 (CC1_32320) 3266656..3267213 + 558 WP_015515294.1 DUF2812 domain-containing protein -
CC1_RS15445 (CC1_32330) 3267301..3267531 + 231 WP_015515295.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
CC1_RS15450 (CC1_32340) 3267528..3267929 + 402 WP_015515296.1 type II toxin-antitoxin system VapC family toxin Toxin
CC1_RS15455 (CC1_32350) 3268173..3269441 - 1269 WP_015515297.1 peptidoglycan-binding domain-containing protein -
CC1_RS15460 (CC1_32360) 3269859..3270944 + 1086 WP_015515298.1 carbamoyl phosphate synthase small subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14977.37 Da        Isoelectric Point: 7.8945

>T29325 WP_015515296.1 NC_021009:3267528-3267929 [Coprococcus catus GD/7]
MRYMLDTNICIYAIKHKPEQAFKRLQEHDPSEICISSVTYAELVHGVEKSKSIEKNRLALALLLANIEIISFDSLAAESY
GKIRADLEKAGNPIGPLDMMIAGHAKSLKYTVVTNNTKEFERVQGLKLENWAK

Download         Length: 402 bp

>T29325 NC_021009:3267528-3267929 [Coprococcus catus GD/7]
ATGAGATATATGCTGGATACCAATATATGTATCTATGCAATAAAGCATAAGCCAGAACAAGCATTTAAGCGGCTGCAAGA
ACACGACCCATCGGAAATATGTATTTCTTCTGTTACATATGCAGAATTGGTACATGGTGTAGAAAAGAGCAAATCAATTG
AAAAGAACAGGCTTGCATTAGCATTATTGTTGGCAAATATTGAAATAATAAGTTTTGACTCTTTAGCTGCTGAAAGTTAT
GGAAAAATTAGAGCTGATTTAGAAAAAGCAGGAAATCCCATTGGACCATTGGATATGATGATTGCAGGACATGCAAAATC
ACTTAAGTATACTGTTGTAACAAATAACACAAAAGAGTTTGAACGGGTACAGGGATTGAAACTTGAAAACTGGGCAAAGT
GA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8890.14 Da        Isoelectric Point: 4.4692

>AT29325 WP_015515295.1 NC_021009:3267301-3267531 [Coprococcus catus GD/7]
MMMAKVFENGRSQAVRLPKECRFNTDEVAVNKIGEIVLLVPKSSKWNSFMQAIDMFSDDFMEDERDNDIKQERESL

Download         Length: 231 bp

>AT29325 NC_021009:3267301-3267531 [Coprococcus catus GD/7]
ATGATGATGGCAAAAGTTTTTGAAAACGGAAGGAGCCAGGCTGTGAGACTGCCAAAAGAATGTAGATTTAACACAGATGA
GGTAGCTGTTAATAAAATTGGGGAAATTGTATTGTTGGTTCCGAAATCAAGTAAATGGAATTCATTTATGCAGGCTATAG
ACATGTTTTCGGATGATTTTATGGAAGATGAGCGAGATAATGATATAAAGCAGGAGCGTGAATCATTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References