293244

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsaAT/-
Location 859968..860445 Replicon chromosome
Accession NZ_LT598688
Organism Staphylococcus aureus isolate Sa_Newman_UoM

Toxin (Protein)


Gene name TsaT Uniprot ID A0A0H3K6W0
Locus tag BN8422_RS04330 Protein ID WP_000052077.1
Coordinates 859968..860156 (-) Length 63 a.a.

Antitoxin (Protein)


Gene name TsaA Uniprot ID T1Y6P8
Locus tag BN8422_RS04335 Protein ID WP_001059690.1
Coordinates 860185..860445 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BN8422_RS04300 856009..856479 + 471 WP_000824472.1 hypothetical protein -
BN8422_RS04305 856820..857506 + 687 WP_001548082.1 thermonuclease family protein -
BN8422_RS04310 857863..858063 + 201 WP_001059082.1 cold-shock protein -
BN8422_RS04315 858559..858777 - 219 WP_000005886.1 hypothetical protein -
BN8422_RS04320 858839..859123 - 285 WP_001004395.1 hypothetical protein -
BN8422_RS04325 859211..859780 - 570 WP_001106654.1 hypothetical protein -
BN8422_RS04330 859968..860156 - 189 WP_000052077.1 hypothetical protein Toxin
BN8422_RS04335 860185..860445 - 261 WP_001059690.1 hypothetical protein Antitoxin
BN8422_RS04340 860786..860989 + 204 WP_000145163.1 sterile alpha motif-like domain-containing protein -
BN8422_RS04345 860986..861222 - 237 WP_000368687.1 hypothetical protein -
BN8422_RS04350 861447..862028 + 582 WP_001140693.1 phosphoglycerate mutase family protein -
BN8422_RS04355 862101..862718 - 618 WP_000255561.1 LysE/ArgO family amino acid transporter -
BN8422_RS04360 862873..863367 - 495 WP_000569884.1 GNAT family N-acetyltransferase -
BN8422_RS04365 863766..864188 - 423 WP_000974460.1 organic hydroperoxide resistance protein -
BN8422_RS04370 864336..865052 + 717 WP_000150017.1 type I 3-dehydroquinate dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 63 a.a.        Molecular weight: 7186.87 Da        Isoelectric Point: 9.9971

>T293244 WP_000052077.1 NZ_LT598688:c860156-859968 [Staphylococcus aureus]
MSLHFAILFWLALIFLVAATFILVLMKKTSKESKKESYLSFTIILYIFGFAILIYTFIFGVL

Download         Length: 189 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9940.09 Da        Isoelectric Point: 4.0624

>AT293244 WP_001059690.1 NZ_LT598688:c860445-860185 [Staphylococcus aureus]
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H3K6W0

Antitoxin

Source ID Structure
AlphaFold DB A0A0E0VN56

References