Detailed information of TA system TA029324

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-Axe/-
• Location: 1615058..1615577
• Replicon: draft genome
• Accession: NC_021009
• Organism: Coprococcus catus GD/7

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: CC1_RS07545
• Protein ID: WP_015513904.1
• Coordinates: 1615314..1615577 (+)
• Length: 88 a.a.

Antitoxin (Protein)

• Gene name: Axe
• Uniprot ID: -
• Locus tag: CC1_RS07540
• Protein ID: WP_015513903.1
• Coordinates: 1615058..1615321 (+)
• Length: 88 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CC1_RS07525 (CC1_15650)	1613414..1613749	-	336	WP_015513900.1	cupin domain-containing protein	-
CC1_RS07530 (CC1_15660)	1613791..1614123	-	333	WP_015513901.1	cupin domain-containing protein	-
CC1_RS07535 (CC1_15670)	1614277..1614981	+	705	WP_015513902.1	RluA family pseudouridine synthase	-
CC1_RS07540 (CC1_15680)	1615058..1615321	+	264	WP_015513903.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
CC1_RS07545 (CC1_15690)	1615314..1615577	+	264	WP_015513904.1	Txe/YoeB family addiction module toxin	Toxin
CC1_RS07550 (CC1_15700)	1615594..1616187	+	594	WP_015513905.1	GNAT family N-acetyltransferase	-
CC1_RS07555 (CC1_15710)	1616227..1617261	+	1035	WP_208728589.1	ATP-binding protein	-
CC1_RS07560 (CC1_15720)	1617783..1619216	+	1434	WP_015513907.1	proline--tRNA ligase	-
CC1_RS07565 (CC1_15730)	1619218..1620144	+	927	WP_015513908.1	LysR family transcriptional regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 88 a.a.
• Molecular weight: 10440.79 Da
• Isoelectric Point: 7.9648

>T29324 WP_015513904.1 NC_021009:1615314-1615577 [Coprococcus catus GD/7]
MNKVFTSNGWEDYIYWQTEDKKTLKKINTLLKDIDRNGNEGIGKPEPLIGNLSGFWSRRINEKDRLIYKIDEYNIYILSC
RYHYSDT

Nucleotide

• Length: 264 bp

>T29324 NC_021009:1615314-1615577 [Coprococcus catus GD/7]
ATGAATAAAGTGTTTACTTCAAATGGATGGGAGGATTACATCTATTGGCAAACTGAAGATAAAAAAACACTGAAGAAGAT
AAATACATTATTAAAAGATATTGATCGGAATGGTAATGAAGGTATCGGAAAACCAGAGCCTCTTATTGGCAATTTATCTG
GATTTTGGAGTCGGAGAATTAATGAAAAGGATAGATTAATTTATAAAATTGACGAGTACAATATTTATATCTTGTCCTGT
CGATATCATTATAGTGATACATAG

Antitoxin

Protein

• Length: 88 a.a.
• Molecular weight: 10286.61 Da
• Isoelectric Point: 4.4341

>AT29324 WP_015513903.1 NC_021009:1615058-1615321 [Coprococcus catus GD/7]
MLAVNYTCLRDNMKRYMDQVTDDYETLIVTRKNNKNVVMMSEEMYNNLMENVHIVSSKANFEWLMQSKQQLTAGNFSQHE
LAEVDDE

Nucleotide

• Length: 264 bp

>AT29324 NC_021009:1615058-1615321 [Coprococcus catus GD/7]
ATGTTGGCTGTAAATTATACTTGCTTACGTGATAATATGAAACGATACATGGATCAAGTGACAGATGATTATGAAACATT
AATTGTTACACGGAAGAATAATAAAAATGTCGTCATGATGTCTGAGGAAATGTACAACAATTTAATGGAGAATGTTCACA
TTGTCAGCAGTAAAGCAAATTTTGAATGGTTAATGCAATCTAAACAGCAATTGACAGCAGGAAATTTTTCACAGCATGAA
TTGGCAGAGGTGGATGATGAATAA