Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relE-Axe/-
Location 1615058..1615577 Replicon draft genome
Accession NC_021009
Organism Coprococcus catus GD/7

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CC1_RS07545 Protein ID WP_015513904.1
Coordinates 1615314..1615577 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name Axe Uniprot ID -
Locus tag CC1_RS07540 Protein ID WP_015513903.1
Coordinates 1615058..1615321 (+) Length 88 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CC1_RS07525 (CC1_15650) 1613414..1613749 - 336 WP_015513900.1 cupin domain-containing protein -
CC1_RS07530 (CC1_15660) 1613791..1614123 - 333 WP_015513901.1 cupin domain-containing protein -
CC1_RS07535 (CC1_15670) 1614277..1614981 + 705 WP_015513902.1 RluA family pseudouridine synthase -
CC1_RS07540 (CC1_15680) 1615058..1615321 + 264 WP_015513903.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CC1_RS07545 (CC1_15690) 1615314..1615577 + 264 WP_015513904.1 Txe/YoeB family addiction module toxin Toxin
CC1_RS07550 (CC1_15700) 1615594..1616187 + 594 WP_015513905.1 GNAT family N-acetyltransferase -
CC1_RS07555 (CC1_15710) 1616227..1617261 + 1035 WP_208728589.1 ATP-binding protein -
CC1_RS07560 (CC1_15720) 1617783..1619216 + 1434 WP_015513907.1 proline--tRNA ligase -
CC1_RS07565 (CC1_15730) 1619218..1620144 + 927 WP_015513908.1 LysR family transcriptional regulator -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-84)

Antitoxin

(1-73)


Sequences


Toxin        


Download         Length: 88 a.a.        Molecular weight: 10440.79 Da        Isoelectric Point: 7.9648

>T29324 WP_015513904.1 NC_021009:1615314-1615577 [Coprococcus catus GD/7]
MNKVFTSNGWEDYIYWQTEDKKTLKKINTLLKDIDRNGNEGIGKPEPLIGNLSGFWSRRINEKDRLIYKIDEYNIYILSC
RYHYSDT

Download         Length: 264 bp

>T29324 NC_021009:1615314-1615577 [Coprococcus catus GD/7]
ATGAATAAAGTGTTTACTTCAAATGGATGGGAGGATTACATCTATTGGCAAACTGAAGATAAAAAAACACTGAAGAAGAT
AAATACATTATTAAAAGATATTGATCGGAATGGTAATGAAGGTATCGGAAAACCAGAGCCTCTTATTGGCAATTTATCTG
GATTTTGGAGTCGGAGAATTAATGAAAAGGATAGATTAATTTATAAAATTGACGAGTACAATATTTATATCTTGTCCTGT
CGATATCATTATAGTGATACATAG

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 10286.61 Da        Isoelectric Point: 4.4341

>AT29324 WP_015513903.1 NC_021009:1615058-1615321 [Coprococcus catus GD/7]
MLAVNYTCLRDNMKRYMDQVTDDYETLIVTRKNNKNVVMMSEEMYNNLMENVHIVSSKANFEWLMQSKQQLTAGNFSQHE
LAEVDDE

Download         Length: 264 bp

>AT29324 NC_021009:1615058-1615321 [Coprococcus catus GD/7]
ATGTTGGCTGTAAATTATACTTGCTTACGTGATAATATGAAACGATACATGGATCAAGTGACAGATGATTATGAAACATT
AATTGTTACACGGAAGAATAATAAAAATGTCGTCATGATGTCTGAGGAAATGTACAACAATTTAATGGAGAATGTTCACA
TTGTCAGCAGTAAAGCAAATTTTGAATGGTTAATGCAATCTAAACAGCAATTGACAGCAGGAAATTTTTCACAGCATGAA
TTGGCAGAGGTGGATGATGAATAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References