Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 449200..449853 Replicon chromosome
Accession NZ_LT594095
Organism Acinetobacter baumannii strain BAL062

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag BAL062_RS02170 Protein ID WP_000607077.1
Coordinates 449464..449853 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag BAL062_RS02165 Protein ID WP_001288210.1
Coordinates 449200..449457 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BAL062_RS02145 444716..445723 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
BAL062_RS02150 445742..446119 + 378 WP_001216380.1 50S ribosomal protein L17 -
BAL062_RS02155 446301..447791 + 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
BAL062_RS02160 447840..449012 - 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
BAL062_RS02165 449200..449457 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
BAL062_RS02170 449464..449853 + 390 WP_000607077.1 membrane protein Toxin
BAL062_RS02175 450623..451708 + 1086 WP_000049106.1 hypothetical protein -
BAL062_RS02180 451786..452352 + 567 WP_000651538.1 rhombosortase -
BAL062_RS02185 452540..454735 + 2196 WP_001158906.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T293210 WP_000607077.1 NZ_LT594095:449464-449853 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT293210 WP_001288210.1 NZ_LT594095:449200-449457 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References