293175

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 2959559..2960169 Replicon chromosome
Accession NZ_LT578417
Organism Cyanobium sp. NIES-981

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag CBM981_RS14845 Protein ID WP_087069028.1
Coordinates 2959559..2959864 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag CBM981_RS14850 Protein ID WP_087069029.1
Coordinates 2959861..2960169 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CBM981_RS14825 2955222..2955628 + 407 Protein_2946 tyrosine-type recombinase/integrase -
CBM981_RS14830 2955824..2956057 + 234 WP_087069026.1 DUF4160 domain-containing protein -
CBM981_RS14835 2956050..2956310 + 261 WP_087069027.1 DUF2442 domain-containing protein -
CBM981_RS15515 2956426..2957400 + 975 WP_157665490.1 hypothetical protein -
CBM981_RS14840 2957515..2958942 + 1428 Protein_2950 IS5 family transposase -
CBM981_RS14845 2959559..2959864 + 306 WP_087069028.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CBM981_RS14850 2959861..2960169 + 309 WP_087069029.1 putative addiction module antidote protein Antitoxin
CBM981_RS14855 2960377..2962041 - 1665 WP_157665491.1 hypothetical protein -
CBM981_RS14865 2963977..2964780 + 804 WP_087067390.1 IS21-like element helper ATPase IstB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2956417..2967223 10806
- flank IS/Tn - - 2957464..2959041 1577


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-83)

Antitoxin

Cro/C1-type helix-turn-helix domain

(48-91)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11108.85 Da        Isoelectric Point: 10.1314

>T293175 WP_087069028.1 NZ_LT578417:2959559-2959864 [Cyanobium sp. NIES-981]
MVEVRQAERFVRWLEGLRDLKGRAKVLARIERLIGGNPGDVRPVGGGVSELRINYGPGYRVYYLQKGTTLIILLAGGDKS
SQAKDIGEALLLAINLSEESR

Download         Length: 306 bp

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 10833.23 Da        Isoelectric Point: 4.5216

>AT293175 WP_087069029.1 NZ_LT578417:2959861-2960169 [Cyanobium sp. NIES-981]
MKPTTSPYDVAEHLRTPEEMAAYLEACIEEADGDAAFIAKALGDIARAQGMTQVARDSGLSRESLYKALSGERSPSFDTI
LKVVSALGLKLSASVRSEAEVA

Download         Length: 309 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References