293171

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1(toxin)
Location 1508019..1508599 Replicon chromosome
Accession NZ_LT578417
Organism Cyanobium sp. NIES-981

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CBM981_RS07715 Protein ID WP_087069278.1
Coordinates 1508237..1508599 (+) Length 121 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CBM981_RS07710 Protein ID WP_087067940.1
Coordinates 1508019..1508240 (+) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CBM981_RS07695 1504396..1504605 - 210 WP_087067938.1 HypC/HybG/HupF family hydrogenase formation chaperone -
CBM981_RS07700 1504565..1507015 - 2451 WP_087067939.1 carbamoyltransferase HypF -
CBM981_RS07705 1507012..1507722 - 711 WP_087069277.1 hydrogenase nickel incorporation protein HypB -
CBM981_RS07710 1508019..1508240 + 222 WP_087067940.1 ribbon-helix-helix domain-containing protein Antitoxin
CBM981_RS07715 1508237..1508599 + 363 WP_087069278.1 type II toxin-antitoxin system VapC family toxin Toxin
CBM981_RS07720 1508609..1508950 - 342 WP_087067941.1 hydrogenase maturation nickel metallochaperone HypA -
CBM981_RS07725 1508943..1509404 - 462 WP_157665377.1 hydrogenase maturation protease -
CBM981_RS07730 1509519..1509707 - 189 WP_087067943.1 hypothetical protein -
CBM981_RS07735 1509897..1511111 + 1215 WP_087067944.1 DUF2235 domain-containing protein -
CBM981_RS07740 1511246..1511449 + 204 WP_087067945.1 hypothetical protein -
CBM981_RS07745 1511510..1512205 + 696 WP_087067946.1 response regulator transcription factor -
CBM981_RS07750 1512309..1513103 - 795 WP_087067947.1 transglutaminase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-103)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-40)


Sequences

Toxin        


Download         Length: 121 a.a.        Molecular weight: 13518.85 Da        Isoelectric Point: 6.4577

>T293171 WP_087069278.1 NZ_LT578417:1508237-1508599 [Cyanobium sp. NIES-981]
MMLLLDTNLLIDVLRGEAVALRWLAEQQRPSISVITWIEVLVGCRQGEQERVEGWLQAFPRLPLDQAVARESVLLRQRHG
LKVPDAIILATARCAGLTLATRNVRDFPLELGDVLHPYTL

Download         Length: 363 bp

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8579.64 Da        Isoelectric Point: 5.8292

>AT293171 WP_087067940.1 NZ_LT578417:1508019-1508240 [Cyanobium sp. NIES-981]
MRTIVDLPEPERAQLDALCRQRGISRAQALREALSQWLEQQRPQHEQVFGLWRDRPEGSLDLQEALRSEWAGR

Download         Length: 222 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References