293169

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1433738..1434528 Replicon chromosome
Accession NZ_LT578417
Organism Cyanobium sp. NIES-981

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag CBM981_RS07295 Protein ID WP_087067877.1
Coordinates 1433738..1434238 (-) Length 167 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag CBM981_RS07300 Protein ID WP_087067878.1
Coordinates 1434235..1434528 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CBM981_RS07260 1429300..1430238 - 939 WP_087067872.1 hypothetical protein -
CBM981_RS07265 1430502..1431616 + 1115 WP_087066678.1 IS3 family transposase -
CBM981_RS07275 1431885..1432295 + 411 WP_087067874.1 hypothetical protein -
CBM981_RS07285 1432604..1432888 + 285 WP_087067875.1 DUF1778 domain-containing protein -
CBM981_RS07290 1432885..1433403 + 519 WP_087067876.1 GNAT family N-acetyltransferase -
CBM981_RS07295 1433738..1434238 - 501 WP_087067877.1 GNAT family N-acetyltransferase Toxin
CBM981_RS07300 1434235..1434528 - 294 WP_087067878.1 DUF1778 domain-containing protein Antitoxin
CBM981_RS07305 1434932..1435348 - 417 WP_087067879.1 hypothetical protein -
CBM981_RS07310 1435357..1435626 - 270 WP_087067880.1 prevent-host-death protein -
CBM981_RS07320 1436381..1436647 - 267 WP_087067881.1 DUF1778 domain-containing protein -
CBM981_RS07325 1436728..1437111 - 384 WP_087067882.1 type II toxin-antitoxin system PemK/MazF family toxin -
CBM981_RS07330 1437108..1437368 - 261 WP_087067883.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
CBM981_RS07335 1437648..1438586 - 939 WP_087067884.1 IS481 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(36-144)

Antitoxin

Vibrio phage ICP1, Orf50

(6-96)


Sequences

Toxin        


Download         Length: 167 a.a.        Molecular weight: 18637.60 Da        Isoelectric Point: 11.5031

>T293169 WP_087067877.1 NZ_LT578417:c1434238-1433738 [Cyanobium sp. NIES-981]
VTWRPPEPLAVQHRLEAFDCGKPTLNHWLFHHARQAQTSGSARTFVVANEENRVVGYFSLTVGQVDTVKAPERIRAGMGR
FPLPVVILARLAVSRENHGRGLGVGMLQDAIRRTLVIADQAGIRAILTHPIDDDAARFYTRFGFITSPLRQQQLLLLLKD
ARKILR

Download         Length: 501 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10629.01 Da        Isoelectric Point: 5.6773

>AT293169 WP_087067878.1 NZ_LT578417:c1434528-1434235 [Cyanobium sp. NIES-981]
MAATGASRPARSARLGLRATPEQEAVLRRAAEVTHKSLTDFILDSACLAAEQTLLDQRLFMVSGSHAQALIDLLDRPEQA
NEGLRDLFTRQAPWDAQ

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References