293154

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX-GNAT
Location 3336629..3337448 Replicon chromosome
Accession NZ_LT556085
Organism Citrobacter amalonaticus strain 92

Toxin (Protein)


Gene name yjhX Uniprot ID A0A3S5G4N2
Locus tag CITRO92_RS16510 Protein ID WP_043001077.1
Coordinates 3336629..3336886 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID -
Locus tag CITRO92_RS16515 Protein ID WP_044258114.1
Coordinates 3336897..3337448 (+) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CITRO92_RS16475 3332434..3333339 - 906 WP_043001082.1 dihydrodipicolinate synthase family protein -
CITRO92_RS16480 3333344..3334132 - 789 WP_043001081.1 IclR family transcriptional regulator -
CITRO92_RS16485 3334368..3335159 + 792 WP_109740146.1 PhzF family phenazine biosynthesis protein -
CITRO92_RS16495 3335641..3336033 + 393 WP_044258118.1 VOC family protein -
CITRO92_RS16500 3336043..3336249 + 207 WP_044258115.1 tryptophan synthase subunit alpha -
CITRO92_RS16510 3336629..3336886 + 258 WP_043001077.1 YjhX family toxin Toxin
CITRO92_RS16515 3336897..3337448 + 552 WP_044258114.1 N-acetyltransferase Antitoxin
CITRO92_RS16520 3337500..3338246 + 747 WP_061070267.1 class I SAM-dependent methyltransferase -
CITRO92_RS16525 3338923..3339507 + 585 WP_044264020.1 hypothetical protein -
CITRO92_RS16530 3339817..3340941 - 1125 WP_109740148.1 N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin

GNAT domain

(18-121)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9490.00 Da        Isoelectric Point: 11.1381

>T293154 WP_043001077.1 NZ_LT556085:3336629-3336886 [Citrobacter amalonaticus]
MNLSRQEQRTLHVLAKGGRIAHVRDASGRVTAVECYSREGLLLADCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QPDNR

Download         Length: 258 bp

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 20365.25 Da        Isoelectric Point: 6.0668

>AT293154 WP_044258114.1 NZ_LT556085:3336897-3337448 [Citrobacter amalonaticus]
MTTRNFTIHITDESDTNDIREVETRAFGYSKEACLVASLLEDDTARPTLSLLARQEGNAVGHILFTRATFKGEMDSPLMH
ILAPLAVIPEYQGRGVGGLLIRTGIEHLRSMGCQCVFVLGHATYYPRHGFEPCAGDKGFPAPYPIAEEHKACWMMQSLSA
QPFDRAGDIQCAQALMKPEHWRE

Download         Length: 552 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3S5G4N2

Antitoxin

Source ID Structure

References