Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 462049..462728 Replicon chromosome
Accession NZ_LT556085
Organism Citrobacter amalonaticus strain 92

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag CITRO92_RS02240 Protein ID WP_109739503.1
Coordinates 462049..462390 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag CITRO92_RS02245 Protein ID WP_109739504.1
Coordinates 462411..462728 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CITRO92_RS02210 457779..458654 + 876 WP_000774153.1 3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase -
CITRO92_RS02215 458703..458993 + 291 WP_044264508.1 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase -
CITRO92_RS02220 459004..459750 + 747 WP_109739500.1 epimerase -
CITRO92_RS02230 460070..460867 - 798 WP_109739501.1 helix-turn-helix transcriptional regulator -
CITRO92_RS02235 461100..461933 - 834 WP_109739502.1 DUF4942 domain-containing protein -
CITRO92_RS02240 462049..462390 - 342 WP_109739503.1 TA system toxin CbtA family protein Toxin
CITRO92_RS02245 462411..462728 - 318 WP_109739504.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
CITRO92_RS02250 462747..462968 - 222 WP_109739505.1 DUF987 domain-containing protein -
CITRO92_RS02255 462977..463453 - 477 WP_109739506.1 RadC family protein -
CITRO92_RS02260 463469..463927 - 459 WP_109739507.1 antirestriction protein -
CITRO92_RS02265 464024..464263 - 240 WP_109739508.1 DUF905 domain-containing protein -
CITRO92_RS02270 464341..464814 - 474 WP_109739509.1 hypothetical protein -
CITRO92_RS02275 464836..465675 - 840 WP_109739510.1 hypothetical protein -
CITRO92_RS02280 465714..466415 - 702 WP_109739511.1 WYL domain-containing protein -
CITRO92_RS02285 466632..467453 - 822 WP_109739512.1 DUF945 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 460070..481237 21167


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-112)

Antitoxin

Antitoxin CbeA

(5-104)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12885.04 Da        Isoelectric Point: 9.9572

>T293147 WP_109739503.1 NZ_LT556085:c462390-462049 [Citrobacter amalonaticus]
MKILPATISRAAKPCLPPVAVWQMLLTRLLEKHYGLTLNDTPFSDEIVIKEHIDAGITLADAVNFLVEKYELVRIDRKGF
SWQEQSPYLRAVDILRARQATGLLRQSRNNAVR

Download         Length: 342 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11796.40 Da        Isoelectric Point: 6.9367

>AT293147 WP_109739504.1 NZ_LT556085:c462728-462411 [Citrobacter amalonaticus]
MSNITWGLQRDITPRLGARLVQEGNRLHYLADRASITGKFSDAECLKLDVAFPHFISQIESMLTTYELNPRHAHCVTLCH
NGFTCEADTLGSCGYVYVAVYSTQR

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References