Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 347085..347739 Replicon chromosome
Accession NZ_LT556085
Organism Citrobacter amalonaticus strain 92

Toxin (Protein)


Gene name cptA Uniprot ID A0A3Q8D714
Locus tag CITRO92_RS01660 Protein ID WP_044254016.1
Coordinates 347085..347492 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A0F6TWP9
Locus tag CITRO92_RS01665 Protein ID WP_042322123.1
Coordinates 347473..347739 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CITRO92_RS01640 342990..344723 - 1734 WP_042999369.1 single-stranded-DNA-specific exonuclease RecJ -
CITRO92_RS01645 344729..345442 - 714 WP_042999368.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
CITRO92_RS01650 345466..346362 - 897 WP_042999367.1 site-specific tyrosine recombinase XerD -
CITRO92_RS01655 346463..346984 + 522 WP_042999366.1 flavodoxin FldB -
CITRO92_RS01660 347085..347492 - 408 WP_044254016.1 protein YgfX Toxin
CITRO92_RS01665 347473..347739 - 267 WP_042322123.1 FAD assembly factor SdhE Antitoxin
CITRO92_RS01670 347996..348976 + 981 WP_109739477.1 tRNA-modifying protein YgfZ -
CITRO92_RS01675 349057..349716 - 660 WP_044264418.1 hemolysin III family protein -
CITRO92_RS01680 349879..350190 - 312 WP_109739478.1 N(4)-acetylcytidine aminohydrolase -
CITRO92_RS01685 350243..350971 + 729 WP_109739479.1 MurR/RpiR family transcriptional regulator -
CITRO92_RS01690 351090..352523 + 1434 WP_109739480.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15863.86 Da        Isoelectric Point: 11.6030

>T293146 WP_044254016.1 NZ_LT556085:c347492-347085 [Citrobacter amalonaticus]
VVLWQSDLRVSWRAQWLSLLLHGLVAAAILLMPWPLSYTPLWLILLSLVVFDCVRSQRRINARQGEVKLLMDGRLRWQGQ
DWLIVSAPWMIKTGMMLRLRSETGKRQHLWLAADSMDKAEWRDLRRLMMQPSTQG

Download         Length: 408 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10544.06 Da        Isoelectric Point: 5.1496

>AT293146 WP_042322123.1 NZ_LT556085:c347739-347473 [Citrobacter amalonaticus]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDTLSDDEKRIFIRLLECDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RDRGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Q8D714

Antitoxin

Source ID Structure
AlphaFold DB A0A0F6TWP9

References