Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeV-yfjZ/CbtA-CbeA
Location 4383856..4384595 Replicon chromosome
Accession NZ_LT556084
Organism Citrobacter amalonaticus strain 86

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag CITRO86_RS21655 Protein ID WP_109739897.1
Coordinates 4384230..4384595 (+) Length 122 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag CITRO86_RS21650 Protein ID WP_109739898.1
Coordinates 4383856..4384194 (+) Length 113 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CITRO86_RS21625 4380317..4381210 + 894 WP_109739902.1 50S ribosome-binding GTPase -
CITRO86_RS21630 4381497..4382174 + 678 WP_109739901.1 hypothetical protein -
CITRO86_RS21635 4382274..4383092 + 819 WP_109739900.1 DUF945 domain-containing protein -
CITRO86_RS21640 4383122..4383622 + 501 WP_174217526.1 DNA repair protein RadC -
CITRO86_RS21645 4383619..4383840 + 222 WP_109739899.1 DUF987 family protein -
CITRO86_RS21650 4383856..4384194 + 339 WP_109739898.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
CITRO86_RS21655 4384230..4384595 + 366 WP_109739897.1 TA system toxin CbtA family protein Toxin
CITRO86_RS21660 4385164..4385532 - 369 WP_023303149.1 TA system toxin CbtA family protein -
CITRO86_RS21665 4385553..4385879 - 327 WP_023303148.1 type IV toxin-antitoxin system YeeU family antitoxin -
CITRO86_RS21670 4385892..4386362 - 471 WP_023303147.1 DNA repair protein RadC -
CITRO86_RS21675 4386428..4387249 - 822 WP_023303146.1 DUF945 domain-containing protein -
CITRO86_RS21685 4387939..4388778 - 840 WP_023303145.1 hypothetical protein -
CITRO86_RS21690 4388837..4389271 - 435 WP_023303144.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4368848..4406797 37949


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(10-111)

Antitoxin

Antitoxin CbeA

(9-108)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 13623.75 Da        Isoelectric Point: 10.6168

>T293143 WP_109739897.1 NZ_LT556084:4384230-4384595 [Citrobacter amalonaticus]
MQISTAPTTVPVSSRLTPIEVWQILLKHLLAQHYGLTLNDTPFSDESTIRQHINAGISLSNAVNFIVEKYELVRTDRSRF
TIMAQSPFISSIEILRARRATGLMKRQGYKSISNITTGHLL

Download         Length: 366 bp

Antitoxin


Download         Length: 113 a.a.        Molecular weight: 12479.25 Da        Isoelectric Point: 7.2412

>AT293143 WP_109739898.1 NZ_LT556084:4383856-4384194 [Citrobacter amalonaticus]
MTKEPVQEHVWGLHSQTVPSFSARLVQEGRRLHFLADRATLLGTFSPEQSATLDAIFPALIRGMETALLSGKLDPRKAKQ
YIYIRNGFACESDTLGSCGYVYIVIYPQSETS

Download         Length: 339 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References