Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 1447837..1448443 Replicon chromosome
Accession NZ_LT549890
Organism Saccharolobus solfataricus strain P1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag SSOP1_RS07845 Protein ID WP_231918326.1
Coordinates 1448108..1448443 (+) Length 112 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag SSOP1_RS07840 Protein ID WP_029552585.1
Coordinates 1447837..1448058 (+) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SSOP1_RS07815 (SSOP1_1615) 1443525..1444781 - 1257 WP_014511659.1 RNA-guided endonuclease TnpB family protein -
SSOP1_RS07820 1444759..1445302 - 544 Protein_1559 IS607 family transposase -
SSOP1_RS16360 1445630..1446297 + 668 Protein_1560 ISNCY family transposase -
SSOP1_RS07835 (SSOP1_1620) 1446706..1447278 - 573 WP_010923431.1 metallophosphoesterase -
SSOP1_RS07840 (SSOP1_1621) 1447837..1448058 + 222 WP_029552585.1 hypothetical protein Antitoxin
SSOP1_RS07845 (SSOP1_1622) 1448108..1448443 + 336 WP_231918326.1 type II toxin-antitoxin system VapC family toxin Toxin
SSOP1_RS07850 (SSOP1_1623) 1448651..1449766 + 1116 WP_009991657.1 hypothetical protein -
SSOP1_RS07855 (SSOP1_1624) 1449910..1450245 - 336 Protein_1565 transposase -
SSOP1_RS17015 1450427..1450572 - 146 Protein_1566 IS630 family transposase -
SSOP1_RS07865 (SSOP1_1625) 1450968..1451465 - 498 WP_014511660.1 hypothetical protein -
SSOP1_RS07870 (SSOP1_1627) 1451607..1452580 - 974 Protein_1568 IS5 family transposase -
SSOP1_RS07875 1452705..1453043 + 339 WP_010923427.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside IScluster/Tn - - 1443525..1456222 12697


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(9-104)

Antitoxin

Putative antitoxin VapB3-like

(1-73)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 12427.61 Da        Isoelectric Point: 5.2389

>T293127 WP_231918326.1 NZ_LT549890:1448108-1448443 [Saccharolobus solfataricus]
IREILKDAETLDFALVEVSNVVWKKAVLTGELTGKDVIKAITIVKEYLPQLLTVNKSIDLIERAIEISVNEKITVYDSLY
IALAECKGSKLVTGDKKQYDVAKKYVISELI

Download         Length: 336 bp

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8959.22 Da        Isoelectric Point: 4.9737

>AT293127 WP_029552585.1 NZ_LT549890:1447837-1448058 [Saccharolobus solfataricus]
MKTVYSLRLDKELREEMEKYNVKWNEEIESFIRKRIEELKKEEILKKINEILQTMPETKSNSADLVREDRDNN

Download         Length: 222 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References