Detailed information of TA system TA293126

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/PIN-AbrB
• Location: 1432611..1433211
• Replicon: chromosome
• Accession: NZ_LT549890
• Organism: Saccharolobus solfataricus strain P1

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: SSOP1_RS07775
• Protein ID: WP_048054229.1
• Coordinates: 1432822..1433211 (+)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: A0A157T1M9
• Locus tag: SSOP1_RS07770
• Protein ID: WP_048054328.1
• Coordinates: 1432611..1432835 (+)
• Length: 75 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	IScluster/Tn	-	-	1425258..1437993	12735

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (2-121)

Antitoxin

• SpoVT-AbrB domain (4-45)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 14446.03 Da
• Isoelectric Point: 4.5625

>T293126 WP_048054229.1 NZ_LT549890:1432822-1433211 [Saccharolobus solfataricus]
MIVVDTNVLIYATLEDSEFHTQSLEIIEGSDIIVPQIVVFEYIKVLSEIVQNLDFIKTKISELNNFVVVCEDLNTIALAL
RLLAELKLSLKDINDMIILTAAIKTNSSIATFDQKLRKIADKKGVKVLP

Nucleotide

• Length: 390 bp

Antitoxin

Protein

• Length: 75 a.a.
• Molecular weight: 8530.93 Da
• Isoelectric Point: 8.5049

>AT293126 WP_048054328.1 NZ_LT549890:1432611-1432835 [Saccharolobus solfataricus]
MISKVTRNFQVTIPYEIRKVLGIKEGDYIEFAIENGKVMIKPVRKVWSTIRLGREVTVEEIEEIASKAFKDDSS

Nucleotide

• Length: 225 bp

Structures

Antitoxin

• AlphaFold DB: A0A157T1M9