293119

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PfiT-PfiA/ParE-Phd
Location 34870..35481 Replicon plasmid p58T1
Accession NZ_LT222313
Organism Pseudomonas cerasi isolate Sour cherry (Prunus cerasus) symptomatic leaf

Toxin (Protein)


Gene name PfiT Uniprot ID A0A193SFX2
Locus tag PCPL58_RS00185 Protein ID WP_065348564.1
Coordinates 34870..35220 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name PfiA Uniprot ID Q6VE98
Locus tag PCPL58_RS00190 Protein ID WP_011152898.1
Coordinates 35233..35481 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PCPL58_RS00170 30992..33757 + 2766 WP_065348562.1 RHS repeat-associated core domain-containing protein -
PCPL58_RS00175 33754..34161 + 408 WP_065348563.1 hypothetical protein -
PCPL58_RS00180 34359..34763 + 405 WP_065348582.1 DUF4279 domain-containing protein -
PCPL58_RS00185 34870..35220 - 351 WP_065348564.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PCPL58_RS00190 35233..35481 - 249 WP_011152898.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PCPL58_RS00195 35813..36775 + 963 WP_065348565.1 tyrosine-type recombinase/integrase -
PCPL58_RS00200 37174..37469 - 296 Protein_41 multicopper oxidase domain-containing protein -
PCPL58_RS00205 37671..38066 - 396 WP_065348566.1 DUF305 domain-containing protein -
PCPL58_RS00210 38398..38601 + 204 WP_005782502.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..101345 101345


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-91)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12947.79 Da        Isoelectric Point: 4.1953

>T293119 WP_065348564.1 NZ_LT222313:c35220-34870 [Pseudomonas cerasi]
MNTFALRFTEVAQQSIEDQVEHLAITQGFSSAAQRIDTLIDAIQDKLLSTPLGYPVSPQLSELGVLHYRELNTDGYRIFY
EVMDSDGITDIAVLLVLGGKQSVEQALIRYCLLQPM

Download         Length: 351 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9329.71 Da        Isoelectric Point: 9.8452

>AT293119 WP_011152898.1 NZ_LT222313:c35481-35233 [Pseudomonas cerasi]
MRVETISYLKRNAADLPLDEPLVVTQNGVPAYVVESYADRKRRDEAIALVKLLAISSREYAQGKHCSTDELKARLSRRFA
HK

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A193SFX2

Antitoxin

Source ID Structure
AlphaFold DB A0A7V8LY57

References