Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-dinJ/YafQ-DinJ
Location 1389522..1390054 Replicon chromosome
Accession NZ_LT220504
Organism Lacticaseibacillus rhamnosus strain BPL5

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BN3853_RS06385 Protein ID WP_061713660.1
Coordinates 1389522..1389806 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag BN3853_RS06390 Protein ID WP_061713661.1
Coordinates 1389803..1390054 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BN3853_RS06370 1386534..1387718 - 1185 WP_005713641.1 methionine adenosyltransferase -
BN3853_RS06375 1387897..1388550 + 654 WP_005688600.1 hypothetical protein -
BN3853_RS06385 1389522..1389806 - 285 WP_061713660.1 type II toxin-antitoxin system YafQ family toxin Toxin
BN3853_RS06390 1389803..1390054 - 252 WP_061713661.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
BN3853_RS06395 1390108..1391406 - 1299 WP_061713662.1 LysM peptidoglycan-binding domain-containing protein -
BN3853_RS06400 1391417..1391830 - 414 WP_005714728.1 phage holin -
BN3853_RS06405 1391845..1392120 - 276 WP_003581984.1 hypothetical protein -
BN3853_RS14695 1392176..1392319 - 144 WP_005688592.1 XkdX family protein -
BN3853_RS06410 1392316..1392645 - 330 WP_005711092.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-81)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10783.56 Da        Isoelectric Point: 8.7304

>T293113 WP_061713660.1 NZ_LT220504:c1389806-1389522 [Lacticaseibacillus rhamnosus]
VSLLKLKYTHSAKKQLKKINLSSEDKDCLEKCLDSLCVGKELPKRYHDHSLSGNWINHREFHLRPNLLVIYSIDGEELIL
TVVAVGRHHNLLGI

Download         Length: 285 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9273.47 Da        Isoelectric Point: 6.2191

>AT293113 WP_061713661.1 NZ_LT220504:c1390054-1389803 [Lacticaseibacillus rhamnosus]
MDKGATINVRTNTDTKRQAKHIAESMGVTLSTAINMFLVEFNKQGKFPFTPTGDLESGIEDEKHGRVSKSFDNAHDMLED
MLK

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References