293099

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsaAT/-
Location 861729..862206 Replicon chromosome
Accession NZ_LT009690
Organism Staphylococcus aureus strain NZAK3

Toxin (Protein)


Gene name TsaT Uniprot ID T1Y7S2
Locus tag NZAK3_RS04210 Protein ID WP_000052076.1
Coordinates 861729..861917 (-) Length 63 a.a.

Antitoxin (Protein)


Gene name TsaA Uniprot ID T1Y6P8
Locus tag NZAK3_RS04215 Protein ID WP_001059690.1
Coordinates 861946..862206 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NZAK3_RS04180 857723..858244 + 522 WP_000824482.1 hypothetical protein -
NZAK3_RS04185 858585..859271 + 687 WP_000141557.1 thermonuclease family protein -
NZAK3_RS04190 859628..859828 + 201 WP_001059082.1 cold-shock protein -
NZAK3_RS04195 860320..860538 - 219 WP_000005886.1 hypothetical protein -
NZAK3_RS04200 860600..860884 - 285 WP_001004399.1 hypothetical protein -
NZAK3_RS04205 860972..861541 - 570 WP_001106654.1 hypothetical protein -
NZAK3_RS04210 861729..861917 - 189 WP_000052076.1 hypothetical protein Toxin
NZAK3_RS04215 861946..862206 - 261 WP_001059690.1 hypothetical protein Antitoxin
NZAK3_RS04220 862547..862750 + 204 WP_000145163.1 sterile alpha motif-like domain-containing protein -
NZAK3_RS04225 862747..862983 - 237 WP_000349581.1 hypothetical protein -
NZAK3_RS04230 863208..863789 + 582 WP_001140693.1 phosphoglycerate mutase family protein -
NZAK3_RS04235 863862..864479 - 618 WP_000255551.1 LysE/ArgO family amino acid transporter -
NZAK3_RS04240 864634..865128 - 495 WP_000569884.1 GNAT family N-acetyltransferase -
NZAK3_RS04245 865527..865949 - 423 WP_000974460.1 organic hydroperoxide resistance protein -
NZAK3_RS04250 866097..866813 + 717 WP_000150011.1 type I 3-dehydroquinate dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 63 a.a.        Molecular weight: 7142.82 Da        Isoelectric Point: 9.9971

>T293099 WP_000052076.1 NZ_LT009690:c861917-861729 [Staphylococcus aureus]
MSLHFAILFWLALIFLVAATFILVLMKKTGKESKKESYLSFTVILYIFGFAILIYTFIFGVL

Download         Length: 189 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9940.09 Da        Isoelectric Point: 4.0624

>AT293099 WP_001059690.1 NZ_LT009690:c862206-861946 [Staphylococcus aureus]
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0E0VP18

Antitoxin

Source ID Structure
AlphaFold DB A0A0E0VN56

References