Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2155037..2155305 Replicon chromosome
Accession NZ_LS999560
Organism Escherichia coli isolate EC-TO143

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2155165..2155267 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2155037..2155305 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ECTO143_RS10495 2151590..2152252 - 663 WP_000944256.1 exodeoxyribonuclease X -
ECTO143_RS10500 2152276..2152932 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
ECTO143_RS10505 2153034..2153264 - 231 WP_000916763.1 DNA polymerase III subunit theta -
ECTO143_RS10510 2153403..2153777 + 375 WP_000168747.1 CopC domain-containing protein YobA -
ECTO143_RS10515 2153781..2154653 + 873 WP_000879317.1 copper homeostasis membrane protein CopD -
ECTO143_RS10520 2154666..2155007 + 342 WP_000976472.1 YebY family protein -
- 2155037..2155305 - 269 - - Antitoxin
- 2155165..2155267 + 103 - - Toxin
ECTO143_RS10525 2155402..2156058 + 657 WP_000812745.1 protein-serine/threonine phosphatase -
ECTO143_RS10530 2156059..2156250 - 192 WP_001296140.1 YebW family protein -
ECTO143_RS10535 2156355..2156591 - 237 WP_001295499.1 DUF1480 family protein -
ECTO143_RS10540 2156708..2158147 - 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T293067 NZ_LS999560:2155165-2155267 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT293067 NZ_LS999560:c2155305-2155037 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References