Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 477967..478620 Replicon chromosome
Accession NZ_LS999521
Organism Acinetobacter calcoaceticus isolate Acinetobacter calcoaceticus str. 2117

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag AC2117_RS02310 Protein ID WP_133971650.1
Coordinates 478231..478620 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID R8YFS6
Locus tag AC2117_RS02305 Protein ID WP_016142980.1
Coordinates 477967..478224 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AC2117_RS02285 473478..474485 + 1008 WP_003653641.1 DNA-directed RNA polymerase subunit alpha -
AC2117_RS02290 474504..474881 + 378 WP_042895180.1 50S ribosomal protein L17 -
AC2117_RS02295 475063..476553 + 1491 WP_133971647.1 NAD(P)/FAD-dependent oxidoreductase -
AC2117_RS02300 476605..477777 - 1173 WP_133971649.1 acyl-CoA dehydrogenase family protein -
AC2117_RS02305 477967..478224 + 258 WP_016142980.1 succinate dehydrogenase assembly factor 2 Antitoxin
AC2117_RS02310 478231..478620 + 390 WP_133971650.1 hypothetical protein Toxin
AC2117_RS02315 479390..480478 + 1089 WP_133971652.1 hypothetical protein -
AC2117_RS02320 480561..481136 + 576 WP_133971654.1 rhombosortase -
AC2117_RS02325 481315..483510 + 2196 WP_133971656.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15441.68 Da        Isoelectric Point: 10.0544

>T293058 WP_133971650.1 NZ_LS999521:478231-478620 [Acinetobacter calcoaceticus]
MIKELNFELKYSRFSIIFQLFIGLSLTILLYQLLSPIWWLIALILLSISFLFFLKQSRISQIAYLDQKLWSVAYSSQKII
SRIEITKIIDYQLFIVIYFEGAPIKVAIIWFDQLPLQDWKKLKILQKVY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10309.76 Da        Isoelectric Point: 4.4909

>AT293058 WP_016142980.1 NZ_LS999521:477967-478224 [Acinetobacter calcoaceticus]
MSDEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELREFIYKLK
QYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0B2UF51

References