Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2859490..2859693 Replicon chromosome
Accession NZ_LS999206
Organism Enterobacter hormaechei isolate EC-TO80

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2859497..2859600 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2859490..2859693 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ECLTO80_RS14090 2855590..2856249 + 660 WP_133982662.1 DNA methyltransferase -
ECLTO80_RS14095 2856246..2856465 + 220 Protein_2723 hypothetical protein -
ECLTO80_RS14100 2856462..2856998 + 537 WP_133982660.1 hypothetical protein -
ECLTO80_RS14105 2856995..2857186 + 192 WP_133982658.1 DUF1382 family protein -
ECLTO80_RS14110 2857183..2857413 + 231 WP_006176201.1 hypothetical protein -
ECLTO80_RS14115 2857505..2857729 + 225 WP_058692128.1 TraR/DksA family transcriptional regulator -
ECLTO80_RS14120 2857738..2857938 - 201 WP_133982949.1 hypothetical protein -
ECLTO80_RS14125 2858093..2858365 + 273 WP_023300430.1 hypothetical protein -
ECLTO80_RS14130 2858334..2859419 + 1086 WP_023300431.1 phage integrase Arm DNA-binding domain-containing protein -
- 2859490..2859693 + 204 - - Antitoxin
- 2859497..2859600 - 104 - - Toxin
ECLTO80_RS14135 2859743..2860081 - 339 WP_033486805.1 YebY family protein -
ECLTO80_RS14140 2860098..2860967 - 870 WP_017384341.1 copper homeostasis membrane protein CopD -
ECLTO80_RS14145 2860969..2861340 - 372 WP_023296802.1 CopC domain-containing protein YobA -
ECLTO80_RS14150 2861478..2861708 + 231 WP_003859784.1 DNA polymerase III subunit theta -
ECLTO80_RS14155 2861820..2862470 + 651 WP_003859783.1 carbon-nitrogen hydrolase family protein -
ECLTO80_RS14160 2862494..2863156 + 663 WP_015570288.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - gtrB 2801545..2865213 63668


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T293048 NZ_LS999206:c2859600-2859497 [Enterobacter hormaechei]
GGCAAGGCGATTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 204 bp

>AT293048 NZ_LS999206:2859490-2859693 [Enterobacter hormaechei]
AATAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTCAATCGCCTTGCCCTTTAAGAATAGATGACGACGTCAGGTTTTCCAGTCCACAGTAAAAGTG
GTCTGAAAAAAAGCGTCAGAACATCACTAAATGTGAAAAACCGC

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References