Detailed information of TA system TA293039

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/-
• Location: 3009288..3010563
• Replicon: chromosome
• Accession: NZ_LS999205
• Organism: Pseudomonas protegens CHA0

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: PPRCHA0_RS14135
• Protein ID: WP_041752203.1
• Coordinates: 3009964..3010563 (+)
• Length: 200 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: PPRCHA0_RS14130
• Protein ID: WP_041752748.1
• Coordinates: 3009288..3009845 (+)
• Length: 186 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PPRCHA0_RS14100	3004540..3005190	+	651	WP_041752197.1	DUF2239 family protein	-
PPRCHA0_RS14105	3005278..3005898	+	621	WP_041752198.1	LysE family translocator	-
PPRCHA0_RS14110	3005944..3006531	-	588	WP_011060980.1	inclusion body family protein	-
PPRCHA0_RS14115	3006943..3008130	+	1188	WP_041752200.1	PrpF protein	-
PPRCHA0_RS14120	3008309..3008776	-	468	WP_051167106.1	hypothetical protein	-
PPRCHA0_RS14125	3008757..3009098	-	342	WP_041752202.1	low molecular weight protein tyrosine phosphatase family protein	-
PPRCHA0_RS14130	3009288..3009845	+	558	WP_041752748.1	helix-turn-helix domain-containing protein	Antitoxin
PPRCHA0_RS14135	3009964..3010563	+	600	WP_041752203.1	HD domain-containing protein	Toxin
PPRCHA0_RS14140	3010778..3012958	+	2181	WP_015635385.1	catalase/peroxidase HPI	-
PPRCHA0_RS14145	3013169..3013627	+	459	WP_015635386.1	hypothetical protein	-
PPRCHA0_RS14150	3013819..3014247	-	429	WP_011060992.1	hypothetical protein	-
PPRCHA0_RS14155	3014482..3015396	+	915	WP_015635387.1	SGNH/GDSL hydrolase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• 5'-deoxynucleotidase YfbR/HDDC2 (8-147)

Antitoxin

• Cro/C1-type helix-turn-helix domain (12-47)

Sequences

Toxin

Protein

• Length: 200 a.a.
• Molecular weight: 22463.25 Da
• Isoelectric Point: 5.3128

>T293039 WP_041752203.1 NZ_LS999205:3009964-3010563 [Pseudomonas protegens CHA0]
MNSELLSGRLDFLREAEKLKDVLRSAHTSSGRQESTAEHSWRLCLMALLFEDQLGDLDLLRVLKLCIVHDLGEAIHGDIP
AVAQAAHPDKSQQERDDLQLLARALDAPAREHLLELWDEYEGAASNEARAVKALDKLETLLQHTQGQNPAGFDYRFNLGY
GRRYTDASPLFQALRQQIDIDTQRCLDAQAQAAVQHRLR

Nucleotide

• Length: 600 bp

Antitoxin

Protein

• Length: 186 a.a.
• Molecular weight: 20497.44 Da
• Isoelectric Point: 7.0311

>AT293039 WP_041752748.1 NZ_LS999205:3009288-3009845 [Pseudomonas protegens CHA0]
MSVALFTSPHLGLALRRWRLLHRVKQQHAAELFGVAQSSISRWENGRQIMEPAERARLEQLLAANLSAAADQALARLVND
SPRAVHLVCDLTHRLLACSATRAGQFGVPLSELLGQSLWGFCTEEITRKEAALDDLGWREVLEPPSLEFFSGHNDSAIVP
IAPSQCRWTRLNLSDGNAVRLVETL

Nucleotide

• Length: 558 bp