Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4992802..4993330 Replicon chromosome
Accession NC_020908
Organism Octadecabacter arcticus 238

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OA238_RS25830 Protein ID WP_044037677.1
Coordinates 4992802..4993092 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OA238_RS25835 Protein ID WP_044037679.1
Coordinates 4993082..4993330 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OA238_RS25800 4988053..4989417 - 1365 WP_044038823.1 ISNCY family transposase -
OA238_RS25805 4989555..4989887 - 333 WP_015497444.1 hypothetical protein -
OA238_RS25810 4990509..4990862 - 354 WP_044037670.1 hypothetical protein -
OA238_RS25815 4990867..4991100 - 234 WP_044037672.1 hypothetical protein -
OA238_RS25820 4991097..4991351 - 255 WP_044037673.1 site-specific DNA-methyltransferase -
OA238_RS30990 4991724..4992173 - 450 WP_083906837.1 redox-sensitive transcriptional activator SoxR -
OA238_RS25825 4992248..4992628 + 381 WP_044037675.1 VOC family protein -
OA238_RS25830 4992802..4993092 - 291 WP_044037677.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OA238_RS25835 4993082..4993330 - 249 WP_044037679.1 plasmid stabilization protein Antitoxin
OA238_RS25840 4993561..4994690 + 1130 Protein_5059 ISAs1 family transposase -
OA238_RS25845 4995303..4997381 + 2079 WP_015497446.1 UPF0149 family protein -
OA238_RS33200 4997363..4997575 + 213 WP_044037681.1 hypothetical protein -
OA238_RS25855 4997839..4998240 - 402 Protein_5062 Tn3 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(9-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11095.98 Da        Isoelectric Point: 10.5948

>T29300 WP_044037677.1 NC_020908:c4993092-4992802 [Octadecabacter arcticus 238]
MSFDLGFIEAALKEWRKLDKTTQSRFKKKLVERCEQPRIPSAKLSGGKDRYKVKLRGVGCRLVYEVKDAEILIVVVAVGR
RDRNDVYNKASQREIP

Download         Length: 291 bp

>T29300 NC_020908:c4993092-4992802 [Octadecabacter arcticus 238]
ATGAGCTTTGATCTCGGTTTTATTGAAGCTGCGCTGAAGGAATGGCGCAAACTCGACAAGACCACCCAGTCTCGGTTCAA
AAAGAAGCTTGTTGAGCGGTGCGAGCAACCTCGCATTCCATCGGCGAAGCTTTCCGGCGGGAAAGACCGCTACAAAGTCA
AACTGCGCGGCGTTGGCTGTCGACTGGTGTACGAGGTCAAAGATGCGGAAATATTGATCGTCGTCGTCGCAGTTGGACGG
CGTGATCGTAACGATGTCTACAACAAGGCCAGTCAGCGCGAGATACCGTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8816.03 Da        Isoelectric Point: 3.9150

>AT29300 WP_044037679.1 NC_020908:c4993330-4993082 [Octadecabacter arcticus 238]
MTYNVMADIAASISELKKNPMGTVAAGEGAAVAILNRNEPAFYCVPAAAYEDMMDRLEDIELNAIADARQGDPIVRVTLD
EL

Download         Length: 249 bp

>AT29300 NC_020908:c4993330-4993082 [Octadecabacter arcticus 238]
ATGACCTACAATGTGATGGCGGACATCGCTGCGAGTATCTCGGAGCTTAAGAAAAACCCCATGGGCACAGTTGCAGCAGG
GGAAGGTGCGGCCGTAGCGATTCTCAATCGAAACGAACCCGCTTTCTACTGCGTGCCTGCTGCGGCGTATGAGGACATGA
TGGATCGGCTTGAGGACATCGAGCTGAACGCGATAGCGGATGCACGCCAAGGCGATCCTATCGTAAGGGTGACGCTGGAT
GAGCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References