Detailed information of TA system TA029298

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-Phd
• Location: 6715089..6715614
• Accession: NC_020895
• Organism: Streptomyces hygroscopicus subsp. jinggangensis TL01

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: SHJGH_RS29715
• Protein ID: WP_041665481.1
• Coordinates: 6715089..6715352 (-)
• Length: 88 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A7G3UBC1
• Locus tag: SHJGH_RS29720
• Protein ID: WP_030744248.1
• Coordinates: 6715345..6715614 (-)
• Length: 90 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SHJGH_RS46185	6711380..6712552	-	1173	WP_158506446.1	restriction endonuclease subunit S	-
SHJGH_RS29710	6712585..6714237	-	1653	WP_014674729.1	type I restriction-modification system subunit M	-
SHJGH_RS29715	6715089..6715352	-	264	WP_041665481.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
SHJGH_RS29720	6715345..6715614	-	270	WP_030744248.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
SHJGH_RS29725	6715743..6716207	-	465	WP_014674732.1	GNAT family N-acetyltransferase	-
SHJGH_RS29730	6716413..6717543	-	1131	WP_014674733.1	DNA polymerase III subunit beta	-
SHJGH_RS29735	6717627..6718130	-	504	WP_014674734.1	hypothetical protein	-
SHJGH_RS29740	6718163..6719029	-	867	WP_014674735.1	amidinotransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (8-85)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (9-58)

Sequences

Toxin

Protein

• Length: 88 a.a.
• Molecular weight: 10017.46 Da
• Isoelectric Point: 7.1643

>T29298 WP_041665481.1 NC_020895:c6715352-6715089 [Streptomyces hygroscopicus subsp. jinggangensis TL01]
VSEYRTVFRPEAQAELRKIPCDMALRILAKLTELESDPLGFNSTALVSQPERRRLRVGDYRIVYTIDNGELVVWVVHVGH
RSTVYDT

Nucleotide

• Length: 264 bp

>T29298 NC_020895:c6715352-6715089 [Streptomyces hygroscopicus subsp. jinggangensis TL01]
GTGAGTGAATACCGAACCGTCTTCCGGCCGGAGGCACAGGCTGAGCTCCGGAAGATCCCTTGCGACATGGCCCTACGCAT
CCTGGCCAAACTGACCGAGCTGGAGAGCGACCCCCTCGGCTTCAACAGCACCGCGCTCGTGTCACAGCCAGAACGCCGTC
GACTGCGGGTCGGCGACTACCGGATCGTCTACACGATCGACAACGGAGAGCTCGTAGTGTGGGTCGTCCACGTCGGGCAT
CGCTCCACCGTTTACGACACCTGA

Antitoxin

Protein

• Length: 90 a.a.
• Molecular weight: 10258.73 Da
• Isoelectric Point: 4.7473

>AT29298 WP_030744248.1 NC_020895:c6715614-6715345 [Streptomyces hygroscopicus subsp. jinggangensis TL01]
MTQPLPIESIRDVRAHLAEVVERADRDDVPTVITRRGKQVAAVVSIEVLRKYQEWEEREINRIIDERMANPAPGIPIEDI
MRETLARGE

Nucleotide

• Length: 270 bp

>AT29298 NC_020895:c6715614-6715345 [Streptomyces hygroscopicus subsp. jinggangensis TL01]
ATGACGCAGCCGCTACCCATAGAGTCCATCCGCGACGTACGTGCGCACCTGGCCGAGGTCGTGGAGCGCGCCGATCGGGA
TGACGTGCCCACCGTGATCACCCGACGGGGCAAGCAAGTCGCCGCCGTCGTCTCCATCGAGGTGCTGCGCAAGTACCAGG
AGTGGGAAGAGCGCGAGATCAACCGGATCATCGACGAACGCATGGCCAACCCGGCACCCGGCATCCCGATCGAGGACATC
ATGAGGGAGACGCTGGCGCGCGGTGAGTGA

Structures

Antitoxin

• AlphaFold DB: A0A7G3UBC1