Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2335312..2335580 Replicon chromosome
Accession NZ_LS992192
Organism Escherichia coli isolate Escherichia coli str. TO217

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2335440..2335542 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2335312..2335580 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ECTO217_RS11785 2331865..2332527 - 663 WP_000944256.1 exodeoxyribonuclease X -
ECTO217_RS11790 2332551..2333207 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
ECTO217_RS11795 2333309..2333539 - 231 WP_000916763.1 DNA polymerase III subunit theta -
ECTO217_RS11800 2333678..2334052 + 375 WP_000168747.1 CopC domain-containing protein YobA -
ECTO217_RS11805 2334056..2334928 + 873 WP_000879317.1 copper homeostasis membrane protein CopD -
ECTO217_RS11810 2334941..2335282 + 342 WP_000976472.1 YebY family protein -
- 2335312..2335580 - 269 - - Antitoxin
- 2335440..2335542 + 103 - - Toxin
ECTO217_RS11815 2335677..2336333 + 657 WP_000812745.1 protein-serine/threonine phosphatase -
ECTO217_RS11820 2336334..2336525 - 192 WP_001296140.1 YebW family protein -
ECTO217_RS11825 2336630..2336866 - 237 WP_001295499.1 DUF1480 family protein -
ECTO217_RS11830 2336983..2338422 - 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2254763..2351419 96656


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T292945 NZ_LS992192:2335440-2335542 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT292945 NZ_LS992192:c2335580-2335312 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References