292846

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 85884..86550 Replicon chromosome
Accession NZ_LS992183
Organism Citrobacter freundii isolate Citrobacter freundii str. U2785

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag CFU2785_RS00460 Protein ID WP_134214823.1
Coordinates 86191..86550 (-) Length 120 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag CFU2785_RS00455 Protein ID WP_134214821.1
Coordinates 85884..86201 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFU2785_RS00420 81295..81612 - 318 WP_054527950.1 CcdB family protein -
CFU2785_RS00425 81612..81905 - 294 WP_003844689.1 type II toxin-antitoxin system CcdA family antitoxin -
CFU2785_RS00430 82002..82367 - 366 WP_134214819.1 hypothetical protein -
CFU2785_RS26200 82499..82672 + 174 WP_032938222.1 hypothetical protein -
CFU2785_RS00435 82806..83060 + 255 Protein_85 transposase -
CFU2785_RS00440 83291..84631 + 1341 WP_008786676.1 IS110 family transposase -
CFU2785_RS00445 84645..85562 + 918 Protein_87 IS3 family transposase -
CFU2785_RS00450 85583..85744 + 162 WP_003841416.1 phage protein -
CFU2785_RS00455 85884..86201 - 318 WP_134214821.1 helix-turn-helix domain-containing protein Antitoxin
CFU2785_RS00460 86191..86550 - 360 WP_134214823.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CFU2785_RS00465 86764..87453 + 690 WP_003841421.1 dipeptidase PepE -
CFU2785_RS00470 87600..89231 - 1632 WP_134214825.1 Na/Pi cotransporter family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-106)

Antitoxin

Cro/C1-type helix-turn-helix domain

(34-87)


Sequences

Toxin        


Download         Length: 120 a.a.        Molecular weight: 13456.53 Da        Isoelectric Point: 10.2555

>T292846 WP_134214823.1 NZ_LS992183:c86550-86191 [Citrobacter freundii]
MTKPLYWVGQARKDLLAMPEHVRDTFGFAFWLAQQGKQHSQTKPLKGFGGAGVLEVVEDYHGSAWRAVYTIQLKNAVYVL
HVFQKKSVSGKATPKPEIDLIYQRLKAAQRHAQESGYVI

Download         Length: 360 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11504.44 Da        Isoelectric Point: 8.9375

>AT292846 WP_134214821.1 NZ_LS992183:c86201-85884 [Citrobacter freundii]
MSYEVEASSGNVYVDLGAYDAEQMQLKAQLAMVIGEILQRKGLTQQQAAQLLGMTQPKLSNLLRGQFRGISEAKMLECLV
RLGRDVEIVVGKEGNMSGKLKVKFG

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References