Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2212193..2212336 Replicon chromosome
Accession NZ_LS992175
Organism Citrobacter freundii isolate Citrobacter freundii str. E2614

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2212228..2212331 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2212193..2212336 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFE2614_RS10990 2208640..2209302 - 663 WP_003034918.1 exodeoxyribonuclease X -
CFE2614_RS10995 2209326..2209982 - 657 WP_003841657.1 carbon-nitrogen hydrolase family protein -
CFE2614_RS11000 2210089..2210319 - 231 WP_003034925.1 DNA polymerase III subunit theta -
CFE2614_RS11005 2210463..2210837 + 375 WP_003034928.1 CopC domain-containing protein YobA -
CFE2614_RS11010 2210841..2211713 + 873 WP_003034931.1 copper homeostasis membrane protein CopD -
CFE2614_RS11015 2211734..2212072 + 339 WP_044700293.1 YebY family protein -
- 2212193..2212336 - 144 - - Antitoxin
- 2212228..2212331 + 104 - - Toxin
CFE2614_RS11020 2212485..2213126 + 642 WP_003034937.1 protein-serine/threonine phosphatase -
CFE2614_RS11025 2213127..2213318 - 192 WP_003034941.1 YebW family protein -
CFE2614_RS11030 2213421..2213657 - 237 WP_029139506.1 DUF1480 family protein -
CFE2614_RS11035 2213758..2215146 - 1389 WP_044700319.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2140241..2220553 80312


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T292797 NZ_LS992175:2212228-2212331 [Citrobacter freundii]
GGCAGGGTAACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 144 bp

>AT292797 NZ_LS992175:c2212336-2212193 [Citrobacter freundii]
CACATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTT
GGCATTAATGCAGGCTAAGTTACCCTGCCATTTAAGAATAGATGACAGCGCCAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References