Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/ParE-DnaT |
Location | 680..1202 | Replicon | plasmid 3 |
Accession | NZ_LS992173 | ||
Organism | Escherichia coli isolate Escherichia coli str. TO73 |
Toxin (Protein)
Gene name | relE | Uniprot ID | G3CAN5 |
Locus tag | ECTO73_RS23985 | Protein ID | WP_000220560.1 |
Coordinates | 680..961 (-) | Length | 94 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | G3CAG1 |
Locus tag | ECTO73_RS23990 | Protein ID | WP_000121743.1 |
Coordinates | 951..1202 (-) | Length | 84 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
ECTO73_RS23980 | 211..534 | - | 324 | WP_001181903.1 | hypothetical protein | - |
ECTO73_RS23985 | 680..961 | - | 282 | WP_000220560.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
ECTO73_RS23990 | 951..1202 | - | 252 | WP_000121743.1 | plasmid stabilization protein | Antitoxin |
ECTO73_RS24000 | 2264..3118 | + | 855 | WP_001239324.1 | replication initiation protein | - |
ECTO73_RS24005 | 3143..3589 | + | 447 | WP_001074386.1 | hypothetical protein | - |
ECTO73_RS24010 | 3657..4082 | + | 426 | WP_015058974.1 | TaxD | - |
ECTO73_RS24015 | 4079..5056 | - | 978 | WP_001579336.1 | hypothetical protein | - |
ECTO73_RS24020 | 5081..5362 | - | 282 | WP_001185482.1 | hypothetical protein | - |
ECTO73_RS24025 | 5462..6124 | - | 663 | WP_000516402.1 | peptidyl-arginine deiminase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | blaTEM-52B | - | 1..16544 | 16544 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | G3CAN5 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3S5I301 |