Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | V | Classification (family/domain) | ghoTS/ghoT-GhoS |
Location | 4505251..4505748 | Replicon | chromosome |
Accession | NZ_LS992168 | ||
Organism | Escherichia coli isolate Escherichia coli str. TO60 |
Toxin (Protein)
Gene name | ghoT | Uniprot ID | L4JJG6 |
Locus tag | ECTO60_RS22560 | Protein ID | WP_001173343.1 |
Coordinates | 4505251..4505424 (-) | Length | 58 a.a. |
Antitoxin (Protein)
Gene name | ghoS | Uniprot ID | S1NQ59 |
Locus tag | ECTO60_RS22565 | Protein ID | WP_001312331.1 |
Coordinates | 4505452..4505748 (-) | Length | 99 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
ECTO60_RS22550 | 4501921..4503378 | + | 1458 | WP_000856826.1 | dipeptide/tripeptide permease DtpC | - |
ECTO60_RS22555 | 4503615..4505132 | + | 1518 | WP_000003806.1 | lysine--tRNA ligase | - |
ECTO60_RS22560 | 4505251..4505424 | - | 174 | WP_001173343.1 | type V toxin-antitoxin system toxin GhoT | Toxin |
ECTO60_RS22565 | 4505452..4505748 | - | 297 | WP_001312331.1 | type V toxin-antitoxin system endoribonuclease antitoxin GhoS | Antitoxin |
ECTO60_RS22570 | 4505976..4506248 | - | 273 | WP_000405647.1 | N-acetyltransferase | - |
ECTO60_RS22575 | 4506462..4510391 | - | 3930 | WP_001080129.1 | autotransporter outer membrane beta-barrel domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | - | 4505251..4521338 | 16087 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7U9QI41 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | S1NQ59 |