Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /Xre(antitoxin) |
| Location | 3980968..3982107 | Replicon | chromosome |
| Accession | NC_020829 | ||
| Organism | Pseudomonas denitrificans ATCC 13867 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | M4XJF1 |
| Locus tag | H681_RS17700 | Protein ID | WP_015478248.1 |
| Coordinates | 3980968..3981738 (-) | Length | 257 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | M4X1H8 |
| Locus tag | H681_RS17705 | Protein ID | WP_015478249.1 |
| Coordinates | 3981739..3982107 (-) | Length | 123 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H681_RS17685 | 3976203..3977093 | + | 891 | WP_015478245.1 | metal-dependent hydrolase | - |
| H681_RS17690 | 3977188..3978528 | + | 1341 | WP_041712672.1 | FAD-binding oxidoreductase | - |
| H681_RS17695 | 3978727..3980091 | - | 1365 | WP_162140839.1 | DNA recombination protein RmuC | - |
| H681_RS17700 | 3980968..3981738 | - | 771 | WP_015478248.1 | RES family NAD+ phosphorylase | Toxin |
| H681_RS17705 | 3981739..3982107 | - | 369 | WP_015478249.1 | DUF2384 domain-containing protein | Antitoxin |
| H681_RS17710 | 3982242..3982724 | + | 483 | WP_015478250.1 | hypothetical protein | - |
| H681_RS17715 | 3982882..3983226 | + | 345 | WP_015478251.1 | carboxymuconolactone decarboxylase family protein | - |
| H681_RS17720 | 3983557..3984492 | - | 936 | WP_041712125.1 | transporter | - |
| H681_RS17725 | 3984692..3985357 | - | 666 | WP_080636235.1 | TetR/AcrR family transcriptional regulator | - |
| H681_RS17730 | 3985545..3986411 | + | 867 | WP_015478255.1 | fumarylacetoacetate hydrolase family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 257 a.a. Molecular weight: 29011.33 Da Isoelectric Point: 9.0074
>T29271 WP_015478248.1 NC_020829:c3981738-3980968 [Pseudomonas sp. ATCC 13867]
MSFETGARIWARHAPESVVGPIRGRLVRLVESQGQVATLQLVDTLAEQALLEELLETSKPRMPPPAEHLHYLLKTPFRYP
PLRWGSRFGRRNEPSLFYAALKLETAMAESAFYRFVLWEGMSSPPPSGRILSEHASFEARFQVQRGVRLQLPPFREYEPA
LRDPLDYRVAQGLGSAMREAGVEAFEYRSARCPHGGVNVALFAPSAFTEKRPRNLMPWLCETTGEYVAFKHAQVPDTPRL
FPRTQFLVDGCLPYPA
MSFETGARIWARHAPESVVGPIRGRLVRLVESQGQVATLQLVDTLAEQALLEELLETSKPRMPPPAEHLHYLLKTPFRYP
PLRWGSRFGRRNEPSLFYAALKLETAMAESAFYRFVLWEGMSSPPPSGRILSEHASFEARFQVQRGVRLQLPPFREYEPA
LRDPLDYRVAQGLGSAMREAGVEAFEYRSARCPHGGVNVALFAPSAFTEKRPRNLMPWLCETTGEYVAFKHAQVPDTPRL
FPRTQFLVDGCLPYPA
Download Length: 771 bp
>T29271 NC_020829:c3981738-3980968 [Pseudomonas sp. ATCC 13867]
ATGTCCTTCGAAACGGGCGCCCGGATCTGGGCACGGCATGCACCGGAGTCGGTCGTCGGTCCGATTCGTGGGCGCCTGGT
GCGCCTGGTGGAGAGCCAGGGCCAGGTAGCCACGCTGCAACTGGTGGACACCCTGGCGGAGCAGGCGCTGCTGGAGGAGT
TGCTGGAAACCAGCAAACCGCGCATGCCGCCGCCTGCCGAGCACCTGCATTATCTATTGAAGACTCCGTTCCGCTATCCC
CCGCTGCGCTGGGGTTCGCGCTTTGGTCGGCGGAATGAGCCGAGTCTCTTCTATGCGGCACTGAAACTGGAAACGGCGAT
GGCCGAGTCGGCCTTCTACCGTTTCGTGCTCTGGGAGGGGATGAGTTCGCCGCCGCCCAGTGGCCGGATTCTTTCCGAGC
ACGCCTCGTTCGAGGCGCGTTTCCAGGTGCAGCGCGGCGTGCGCCTGCAGTTGCCGCCGTTCCGCGAGTACGAGCCGGCG
CTGCGCGATCCGTTGGACTACCGGGTTGCCCAGGGCCTGGGTAGCGCGATGCGCGAGGCCGGGGTGGAGGCGTTCGAATA
TCGCTCGGCACGCTGTCCGCACGGCGGGGTCAACGTCGCATTGTTCGCCCCATCGGCATTCACCGAGAAGCGTCCGCGCA
ACCTGATGCCCTGGCTGTGCGAGACCACGGGGGAGTATGTCGCCTTCAAGCACGCCCAGGTGCCGGACACGCCGCGATTG
TTCCCGCGCACGCAGTTCCTGGTGGACGGGTGCCTCCCGTATCCCGCCTGA
ATGTCCTTCGAAACGGGCGCCCGGATCTGGGCACGGCATGCACCGGAGTCGGTCGTCGGTCCGATTCGTGGGCGCCTGGT
GCGCCTGGTGGAGAGCCAGGGCCAGGTAGCCACGCTGCAACTGGTGGACACCCTGGCGGAGCAGGCGCTGCTGGAGGAGT
TGCTGGAAACCAGCAAACCGCGCATGCCGCCGCCTGCCGAGCACCTGCATTATCTATTGAAGACTCCGTTCCGCTATCCC
CCGCTGCGCTGGGGTTCGCGCTTTGGTCGGCGGAATGAGCCGAGTCTCTTCTATGCGGCACTGAAACTGGAAACGGCGAT
GGCCGAGTCGGCCTTCTACCGTTTCGTGCTCTGGGAGGGGATGAGTTCGCCGCCGCCCAGTGGCCGGATTCTTTCCGAGC
ACGCCTCGTTCGAGGCGCGTTTCCAGGTGCAGCGCGGCGTGCGCCTGCAGTTGCCGCCGTTCCGCGAGTACGAGCCGGCG
CTGCGCGATCCGTTGGACTACCGGGTTGCCCAGGGCCTGGGTAGCGCGATGCGCGAGGCCGGGGTGGAGGCGTTCGAATA
TCGCTCGGCACGCTGTCCGCACGGCGGGGTCAACGTCGCATTGTTCGCCCCATCGGCATTCACCGAGAAGCGTCCGCGCA
ACCTGATGCCCTGGCTGTGCGAGACCACGGGGGAGTATGTCGCCTTCAAGCACGCCCAGGTGCCGGACACGCCGCGATTG
TTCCCGCGCACGCAGTTCCTGGTGGACGGGTGCCTCCCGTATCCCGCCTGA
Antitoxin
Download Length: 123 a.a. Molecular weight: 13393.64 Da Isoelectric Point: 9.7742
>AT29271 WP_015478249.1 NC_020829:c3982107-3981739 [Pseudomonas sp. ATCC 13867]
MSALLRESPAADAVLAKAVLTAREHLAMTQQELAAIVGVDRSAVSRWKQGGLRVDSKTGELALLLVRVYRALFALFGGNL
EDMRHFLRTENRHLSGVPLQLMEQVQGLVAVVEYLDAIRGKV
MSALLRESPAADAVLAKAVLTAREHLAMTQQELAAIVGVDRSAVSRWKQGGLRVDSKTGELALLLVRVYRALFALFGGNL
EDMRHFLRTENRHLSGVPLQLMEQVQGLVAVVEYLDAIRGKV
Download Length: 369 bp
>AT29271 NC_020829:c3982107-3981739 [Pseudomonas sp. ATCC 13867]
ATGAGTGCCCTGTTACGCGAAAGCCCCGCAGCCGATGCCGTACTGGCCAAGGCGGTACTCACGGCTCGCGAACATCTGGC
GATGACCCAGCAGGAACTGGCGGCGATCGTAGGGGTGGACCGTAGCGCCGTCAGCCGCTGGAAGCAAGGCGGTCTGCGGG
TGGACAGCAAGACCGGCGAACTGGCCCTGTTGCTGGTGCGGGTCTATCGCGCGCTGTTTGCCCTGTTCGGCGGCAATCTG
GAGGACATGCGCCACTTCCTGCGTACCGAGAACCGTCACTTGAGCGGCGTGCCGCTGCAGTTGATGGAGCAAGTGCAGGG
GCTGGTGGCGGTGGTCGAATATCTGGATGCCATCCGGGGCAAGGTCTGA
ATGAGTGCCCTGTTACGCGAAAGCCCCGCAGCCGATGCCGTACTGGCCAAGGCGGTACTCACGGCTCGCGAACATCTGGC
GATGACCCAGCAGGAACTGGCGGCGATCGTAGGGGTGGACCGTAGCGCCGTCAGCCGCTGGAAGCAAGGCGGTCTGCGGG
TGGACAGCAAGACCGGCGAACTGGCCCTGTTGCTGGTGCGGGTCTATCGCGCGCTGTTTGCCCTGTTCGGCGGCAATCTG
GAGGACATGCGCCACTTCCTGCGTACCGAGAACCGTCACTTGAGCGGCGTGCCGCTGCAGTTGATGGAGCAAGTGCAGGG
GCTGGTGGCGGTGGTCGAATATCTGGATGCCATCCGGGGCAAGGTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|