Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | abiEi-abiEii/AbiEii-AbiEi |
Location | 1056246..1057679 | Replicon | chromosome |
Accession | NZ_LS483518 | ||
Organism | Mycoplasma mycoides subsp. capri strain GM12 isolate synthetic |
Toxin (Protein)
Gene name | abiEii | Uniprot ID | - |
Locus tag | EXZ43_RS04530 | Protein ID | WP_080511208.1 |
Coordinates | 1056246..1056980 (-) | Length | 245 a.a. |
Antitoxin (Protein)
Gene name | abiEi | Uniprot ID | A0A7Z7PN10 |
Locus tag | EXZ43_RS04535 | Protein ID | WP_020863064.1 |
Coordinates | 1057080..1057679 (-) | Length | 200 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
EXZ43_RS04515 | 1052542..1054119 | - | 1578 | WP_020863062.1 | dicarboxylate/amino acid:cation symporter | - |
EXZ43_RS04520 | 1054139..1055482 | - | 1344 | WP_023905986.1 | CoA-disulfide reductase | - |
EXZ43_RS04525 | 1055700..1056200 | + | 501 | WP_020863063.1 | isochorismatase family protein | - |
EXZ43_RS04530 | 1056246..1056980 | - | 735 | WP_080511208.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
EXZ43_RS04535 | 1057080..1057679 | - | 600 | WP_020863064.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
EXZ43_RS04540 | 1057947..1058066 | + | 120 | Protein_836 | isochorismatase family protein | - |
EXZ43_RS04545 | 1058256..1059590 | + | 1335 | WP_020863065.1 | DUF285 domain-containing protein | - |
EXZ43_RS04775 | 1059840..1061063 | + | 1224 | WP_020863066.1 | phosphatase PAP2 family protein | - |
EXZ43_RS04560 | 1061194..1062399 | + | 1206 | WP_020863067.1 | phosphatase PAP2 family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 245 a.a. Molecular weight: 28915.65 Da Isoelectric Point: 9.5052
>T292691 WP_080511208.1 NZ_LS483518:c1056980-1056246 [Mycoplasma mycoides subsp. capri]
MKKISKNKDKINIIFKGGFLLSNIIGIKERTTKDIDYLLNNIVFSPDRIKELFEDILDYKKGDKIHFQIQKINEIKKKEK
YTGFRITVECKLDEIVEIIKIDVATGDIITSCQVRYNIENIFHNNSFYVYGYNLETMLAEKIHAIKELSLFNTRTKDFYD
IYLIYNLKRDDIDYMTLKNACINTFKQRNSIFDKDDLLELLNKIKNSQSTHNLTKQKNIYFYNKNIDFKFIIQSIIELIK
NIK
MKKISKNKDKINIIFKGGFLLSNIIGIKERTTKDIDYLLNNIVFSPDRIKELFEDILDYKKGDKIHFQIQKINEIKKKEK
YTGFRITVECKLDEIVEIIKIDVATGDIITSCQVRYNIENIFHNNSFYVYGYNLETMLAEKIHAIKELSLFNTRTKDFYD
IYLIYNLKRDDIDYMTLKNACINTFKQRNSIFDKDDLLELLNKIKNSQSTHNLTKQKNIYFYNKNIDFKFIIQSIIELIK
NIK
Download Length: 735 bp
Antitoxin
Download Length: 200 a.a. Molecular weight: 23847.67 Da Isoelectric Point: 8.3457
>AT292691 WP_020863064.1 NZ_LS483518:c1057679-1057080 [Mycoplasma mycoides subsp. capri]
MNYVEKIKEKAIQNNGLITRKEIISLKIPPIYITRMVRKKELEKIDIGIYALTSLDNYPYDPEFNFCSRYQVPVFSYVYA
LNLFDFTDVIPLNFEVTVYKGYNAHNLKPNTIVHYVNKEIFNLGITEIRNAFGNWVRTYDIERTICDLIKNRKNINVELF
VKTMNNYVNYEKKDWNKLYEYAEKMHIEKELVEIFQLII
MNYVEKIKEKAIQNNGLITRKEIISLKIPPIYITRMVRKKELEKIDIGIYALTSLDNYPYDPEFNFCSRYQVPVFSYVYA
LNLFDFTDVIPLNFEVTVYKGYNAHNLKPNTIVHYVNKEIFNLGITEIRNAFGNWVRTYDIERTICDLIKNRKNINVELF
VKTMNNYVNYEKKDWNKLYEYAEKMHIEKELVEIFQLII
Download Length: 600 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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