Detailed information of TA system TA029269

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii-AbiEi
• Location: 951666..953194
• Replicon: chromosome
• Accession: NC_020829
• Organism: Pseudomonas denitrificans ATCC 13867

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: M4WRP2
• Locus tag: H681_RS04410
• Protein ID: WP_015475633.1
• Coordinates: 951666..952583 (-)
• Length: 306 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: -
• Locus tag: H681_RS25630
• Protein ID: WP_015475634.1
• Coordinates: 952580..953194 (-)
• Length: 205 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
H681_RS25625	947744..947965	-	222	WP_080636197.1	helix-turn-helix domain-containing protein	-
H681_RS04395	948070..948660	+	591	WP_015475630.1	hypothetical protein	-
H681_RS04400	948657..950057	+	1401	WP_015475631.1	DEAD/DEAH box helicase family protein	-
H681_RS04405	950295..951566	-	1272	WP_015475632.1	RES family NAD+ phosphorylase	-
H681_RS04410	951666..952583	-	918	WP_015475633.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
H681_RS25630	952580..953194	-	615	WP_015475634.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	Antitoxin
H681_RS04425	953278..957336	+	4059	WP_041711725.1	helix-turn-helix domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	948070..962683	14613

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (39-274)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (11-55)

Sequences

Toxin

Protein

• Length: 306 a.a.
• Molecular weight: 34532.60 Da
• Isoelectric Point: 6.0465

>T29269 WP_015475633.1 NC_020829:c952583-951666 [Pseudomonas sp. ATCC 13867]
MSVKGVKNAAASISARLLNLARQRGDSFQHIQTRYALERLLFRISQTPEAAGYVLKGAMLFVTWPEHVYRPTRDIDLLGH
GDPSPDAILELFRKICRVEVLEDGITFDPTTLSIQPVRERDRYQGICLSLEGQMGSARIPVQVDIGFGDHVYPEPEPQNF
PNLLPGLPQARILMYPPETVVAEKFEAMVRFGGLNSRLKDFHDIWVIIRTFSVDLSTLLRAITGTFQRRDATVPADIPLG
LTPAFAETAGELWQGFLRRNPPTYQLPPFEDLLAELRQFFGPAIASFERQEFAQGLWDPDRRSWL

Nucleotide

• Length: 918 bp

>T29269 NC_020829:c952583-951666 [Pseudomonas sp. ATCC 13867]
ATGAGCGTAAAAGGCGTTAAGAACGCGGCAGCGTCAATCAGTGCCCGCCTGCTGAATTTGGCCAGACAGCGAGGCGACAG
TTTTCAACACATCCAAACTCGCTATGCCCTGGAGCGGTTGCTGTTTCGCATTAGCCAAACACCCGAGGCAGCGGGCTACG
TGCTCAAAGGCGCGATGCTGTTCGTGACCTGGCCAGAGCACGTGTATCGCCCAACAAGGGACATTGATCTACTTGGCCAC
GGAGACCCCAGCCCGGATGCGATTCTTGAGCTGTTTCGGAAAATCTGCCGGGTAGAAGTCCTAGAGGACGGTATTACCTT
CGATCCCACCACTCTGTCTATTCAGCCAGTGAGAGAGAGGGACAGGTACCAAGGGATCTGTCTCAGCCTGGAGGGGCAAA
TGGGCTCCGCAAGGATACCCGTGCAGGTCGATATCGGTTTTGGTGATCATGTGTACCCTGAACCTGAACCGCAAAACTTT
CCCAATCTCCTGCCAGGGCTGCCTCAAGCCCGCATCCTGATGTATCCGCCAGAAACTGTGGTCGCGGAGAAATTCGAGGC
GATGGTCCGTTTCGGTGGGCTCAACAGCAGGCTAAAAGATTTCCACGATATCTGGGTCATCATCCGTACTTTCTCCGTTG
ACCTGTCGACCCTGCTCCGGGCGATCACGGGAACTTTTCAGCGCCGCGATGCAACTGTCCCGGCGGACATCCCCTTGGGG
CTAACCCCGGCCTTTGCTGAGACCGCCGGGGAGCTGTGGCAAGGCTTCCTACGCCGCAATCCGCCAACCTACCAGCTGCC
ACCATTTGAGGATCTACTAGCTGAGCTACGCCAGTTCTTCGGTCCGGCGATAGCTAGTTTCGAACGCCAGGAGTTCGCAC
AAGGTCTGTGGGATCCTGATCGCAGGTCATGGCTTTGA

Antitoxin

Protein

• Length: 205 a.a.
• Molecular weight: 22800.37 Da
• Isoelectric Point: 9.4230

>AT29269 WP_015475634.1 NC_020829:c953194-952580 [Pseudomonas sp. ATCC 13867]
MAENDMTHRERALRLVQDMGIVRARDFTAAGIPLVYLKRLCDSGDIFRLARGLYQDPNRLGEDAAHDLAEAARRVPNGVI
SLISALHYHQLTTQLPHAVWMTIPHKARTPTPQGLRLEIVRATGEVMSAGIEHVRVEGVEIPIYCVAKTVADCFKHRRHV
GEDVAIEALKDALQKQKTNPSDLMRYAAINRVAGRIAPYIRALQ

Nucleotide

• Length: 615 bp

>AT29269 NC_020829:c953194-952580 [Pseudomonas sp. ATCC 13867]
ATGGCTGAAAACGATATGACTCATCGGGAGCGAGCCCTACGCCTTGTCCAGGATATGGGCATCGTACGCGCACGCGATTT
CACCGCTGCCGGCATCCCTCTGGTTTACCTGAAACGCCTCTGCGACTCCGGCGATATTTTCCGCCTCGCCCGAGGGCTCT
ACCAAGACCCCAATCGCCTGGGTGAGGACGCCGCTCACGATCTGGCCGAAGCAGCTCGCCGAGTGCCCAATGGAGTCATC
AGCCTTATCAGCGCTCTCCACTATCACCAGCTCACCACCCAGCTCCCCCACGCGGTCTGGATGACAATCCCCCACAAAGC
TAGGACACCTACCCCTCAGGGACTACGACTGGAAATCGTGCGCGCCACTGGCGAGGTAATGTCCGCCGGCATTGAGCATG
TCCGCGTCGAAGGCGTGGAAATACCAATCTACTGTGTAGCCAAAACCGTGGCGGATTGCTTCAAACACCGACGGCATGTG
GGTGAGGACGTAGCGATAGAGGCGCTGAAAGACGCCCTTCAAAAGCAGAAAACGAATCCCAGCGATTTGATGCGGTACGC
AGCTATCAATCGCGTGGCTGGACGGATTGCTCCCTACATAAGGGCCCTTCAATGA

Structures

Toxin

• AlphaFold DB: M4WRP2