Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Fic-relB/Fic-DinJ
Location 885616..886530 Replicon chromosome
Accession NZ_LS483510
Organism Mycoplasma mycoides subsp. capri strain GM12 isolate synthetic

Toxin (Protein)


Gene name Fic Uniprot ID -
Locus tag EXZ31_RS03845 Protein ID WP_129880435.1
Coordinates 885616..886173 (+) Length 186 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EXZ31_RS03850 Protein ID WP_129880436.1
Coordinates 886258..886530 (+) Length 91 a.a.

Genomic Context

EXZ31_RS03845EXZ31_RS03850EXZ31_RS03865EXZ31_RS03840EXZ31_RS03855EXZ31_RS03860
Location: 885616..886173 (558 bp)
Type: Toxin
Protein ID: WP_129880435.1
Location: 886258..886530 (273 bp)
Type: Antitoxin
Protein ID: WP_129880436.1
Location: 888508..890547 (2040 bp)
Type: Others
Protein ID: WP_020862964.1
Location: 882289..885254 (2966 bp)
Type: Others
Protein ID: Protein_699
Location: 886569..887310 (742 bp)
Type: Others
Protein ID: Protein_702
Location: 887303..888391 (1089 bp)
Type: Others
Protein ID: WP_020862963.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EXZ31_RS03840882289..885254-2966Protein_699viral A-type inclusion protein-
EXZ31_RS03845885616..886173+558WP_129880435.1Fic family proteinToxin
EXZ31_RS03850886258..886530+273WP_129880436.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
EXZ31_RS03855886569..887310-742Protein_702DNA adenine methylase-
EXZ31_RS03860887303..888391-1089WP_020862963.1DNA adenine methylase-
EXZ31_RS03865888508..890547+2040WP_020862964.1AlwI family type II restriction endonuclease-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Fido domain

(37-116)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-79)


Sequences

Toxin        


Download         Length: 186 a.a.        Molecular weight: 21402.77 Da        Isoelectric Point: 7.8918

>T292682 WP_129880435.1 NZ_LS483510:885616-886173 [Mycoplasma mycoides subsp. capri]
MKANFLEEEFEINLSVKHLLELDKNLLNTFEIGTFKGLSQIHSYMFKDIFDFNGQIRNVNISKNNSMFCLARYLKQNLEI
IDNMKHDTFDQIIDKYVEMNICHPFREGNGRSMRILDLILKKQLNVVVNTNINKDEYLLAMINSLIDSTNLKLLIKNNLT
NKITDRNVYINNSFDIKNLKSF

Download         Length: 558 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10451.07 Da        Isoelectric Point: 8.4491

>AT292682 WP_129880436.1 NZ_LS483510:886258-886530 [Mycoplasma mycoides subsp. capri]
MKKVNVNIKMDPEIKKQASLLFKEFGMTMSSAINLFVKTAVEQNDIPFEYNREITNKETLEAFKEGERLLADKNAKRYSS
FKEILDSLDK

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References